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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11857 | LIT-001 | Oxytocin Receptor | |
LIT-001 improves social interaction in a mouse model of autism.It is the first nonpeptide oxytocin receptor agonist with EC50 of 55 nM and Ki of 226 nM. | |||
T14782 | Brilaroxazine | RP5063 | Dopamine Receptor , 5-HT Receptor |
Brilaroxazine (RP5063) is a potent multimodal dopamine/5-HT modulator. Brilaroxazine is a partial agonist of dopamine D2, D3, and D4 receptors, 5-HT1A (Ki =1.5 nM) and 5-HT2A (Ki = 2.5 nM), and has antagonist activity 5-... | |||
T50112 | 5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine dihydrochloride | Others | |
5-(2-aminoethyl)-4-methyl-1,3-thiazol-2-amine dihydrochloride is a potent and selective antagonist of metabotropic glutamate receptor 5 (mGluR5). It has been shown to be effective in several neurological disorders, inclu... | |||
T39252 | TAK-418 | Histone Demethylase | |
TAK-418 is a selective and orally active inhibitor of LSD1/KDM1A enzyme with an IC50 of 2.9 nM. TAK-418 unlocks abnormal epigenetic mechanisms and improves autism symptoms in models of neurodevelopmental disorders. | |||
T14494 | Balovaptan | RG7314 | Vasopressin Receptor |
Balovaptan (RG7314) is a highly potent and selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors. It is used for the research of autism. | |||
T4120 | N-Methylsarcosine | N,N-Dimethylglycine,N,N-Dimethylaminoacetic acid,Dimethylglycine,DMG | Endogenous Metabolite |
N-Methylsarcosine (Dimethylglycine) is used as an athletic performance enhancer and immunostimulant. It is also used in the treatment of autism, epilepsy and mitochondrial disease. It is also employed as a biomarker of p... | |||
T11856 | LIT-001 free base | Others | |
LIT-001 free base improves social interaction in a mouse model of autism. LIT-001 free base is the first nonpeptide oxytocin receptor (OT-R) agonist (EC50=55 nM; Ki=226 nM). |