acyl — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T40707	Methyl-PEG4-acyl chloride	Methyl-PEG4-acyl chloride
	Methyl-PEG4-acyl chloride is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasom...
T11843	Levothyroxine acyl glucuronide	Thyroxine acyl-β-D-glucuronide	Others
	Levothyroxine acyl glucuronide (Thyroxine Acyl-β-D-glucuronide), the acyl glucuronide formation of thyroxine (T4), an endogenous metabolite.		Others
T37117	Etodolac Acyl Glucuronide
	Etodolac acyl glucuronide is a phase II metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor etodolac .1It is formedviaglucuronidation of etodolac by the UDP-glucuronosyltransferase (UGT) isof...
T35621	Febuxostat Acyl Glucuronide
	Febuxostat acyl glucuronide is a metabolite of the xanthine oxidoreductase inhibitor febuxostat . Febuxostat acyl glucuronide is formed via glucuronidation of febuxostat by uridine diphosphate-glucuronosyltransferases (U...
TP1837	Acyl Carrier Protein (ACP) (65-74)	Acyl Carrier Protein (ACP) 65-74
	Acyl Carrier Protein (ACP) (65-74) is an active acyl carrier protein (ACP) fragment.Acyl Carrier Protein (ACP) is a component of plastid-located plant fatty acid synthetase. It binds acyl groups covalently via the prosth...
T40832	Ferulic acid acyl-β-D-glucoside	Ferulic acid glucoside,Ferulic acid acyl-β-D-glucoside
	Ferulic acid acyl-β-D-glucoside, a metabolite of Ferulic Acid, is a novel inhibitor of fibroblast growth factor receptor 1 (FGFR1). It exhibits IC50 values of 3.78 µM and 12.5 µM for FGFR1 and FGFR2, respectively.
T83873	Dabigatran Acyl-β-D-Glucuronide TFA	Dabigatran β-1-O-Acyl Glucuronide
	Dabigatran acyl-β-D-glucuronide, an active metabolite of the thrombin inhibitor dabigatran, is synthesized predominantly through the action of the UDP-glucuronosyltransferase isoform UGT2B15. This compound, at a concentr...
T13060	T3 Acyl glucuronide		Others
	T3 Acyl glucuronide is the acyl glucuronide formation of triiodothyronine (T3). T3 Acyl glucuronide is an endogenous metabolite		Others
T35939	Dabigatran Acyl-β-D-Glucuronide
	Dabigatran acyl-β-D-glucuronide is a major active metabolite of the thrombin inhibitor dabigatran . The prodrug of dabigatran, dabigatran etexilate , is hydrolyzed by plasma esterases to form dabigatran, which is metabol...
T40557	Simvastatin Acyl-β-D-glucuronide
	Simvastatin Acyl-β-D-glucuronide, a metabolite formed from Simvastatin, acts as a competitive inhibitor of HMG-CoA reductase, showcasing a potent Ki of 0.2 nM.
T35865	Telmisartan Acyl-β-D-Glucuronide
	Telmisartan acyl-β-D-glucuronide is a major metabolite of the angiotensin II receptor antagonist telmisartan . It does not bind human serum albumin and is cleared from rat plasma with a clearance rate of 180 ml/min/kg fo...
T27167	Diclofenac Acyl Glucuronide
	Diclofenac Acyl Glucuronide is a major biliary metabolite of Diclofenac (GLXC-07892), a nonsteroidal antiinflammatory drug and COX inhibitor.
T37251	Celecoxib Carboxylic Acid Acyl-β-D-Glucuronide
	Celecoxib carboxylic acid acyl-β-D-glucuronide is a phase II metabolite of celecoxib . Celecoxib is an anti-inflammatory compound from the diaryl heterocycle class that selectively inhibits cyclooxygenase-2 (COX-2; IC50s...
T76124	Acyl coenzyme A synthetase
	Acyl coenzyme A synthetase (ACS), also known as acetyl coenzyme A synthetase, plays a pivotal role in biochemical research. This enzyme catalyzes the activation of fatty acids via coenzyme A through a two-step thioesteri...
T75685	UDP-3-O-acyl-GlcNAc
	UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine), an E. coli metabolite, plays a role in the 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway [1].
T80020	UDP-3-O-acyl-GlcNAc diammonium	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine diammonium	Endogenous Metabolite
	UDP-3-O-acyl-GlcNAc diammonium serves as a metabolite in E. coli, playing a critical role in the biosynthesis pathway of 3-deoxy-D-manno-octulosonate (KDO) [1].		Endogenous Metabolite
T78136	Perindopril acyl-β-D-glucuronide		Drug Metabolite
	Perindopril acyl-β-D-glucuronide is a metabolite of the ACE inhibitor perindopril [1].		Drug Metabolite
T16129	MPI_5a		HDAC
	MPI_5a is an effective and selective inhibitor of HDAC6 (IC50=36 nM). MPI_5a weakly inhibits other HDAC isoforms and it also inhibits acyl-tubulin accumulation in cells (IC50: 210 nM).		HDAC
T23521	VULM 1457		Acyltransferase
	VULM 1457 is a potent ACAT inhibitor. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM1457 significantly reduces production and secretion of...		Acyltransferase
T13373	YM17E		Acyltransferase , AChR
	YM17E is an inhibitor of ACAT with IC50 of 44 nM in rabbit liver microsomes in vitro.		Acyltransferase , AChR