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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T19723 | AMTB hydrochloride | AMTB | TRP/TRPV Channel |
AMTB hydrochloride (AMTB HCl) is a novel TRPM8 channel blocker and is effective for pain and urinary diseases. AMTB can act on the bladder afferent pathway to attenuate the bladder micturition reflex and nociceptive refl... | |||
T15260 | Evenamide | NW-3509 | Sodium Channel |
Evenamide (NW-3509) is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness. | |||
T0939 | Phenytoin | Diphenylhydantoin,5,5-Diphenylhydantoin | Virus Protease , Sodium Channel |
Phenytoin (5,5-Diphenylhydantoin) is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux from neurons located in the motor cor... | |||
T4497 | Amifampridine | 3,4-Pyridinediamine,Pyridine-3,4-Diamine,3,4-Diaminopyridine | Others |
Amifampridine (3,4-Diaminopyridine) is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is ... | |||
T7806 | Licarbazepine | 10,11-hydroxy-10,11 Dihydrocarbamezer | Others |
Licarbazepine (10,11-hydroxy-10,11 Dihydrocarbamezer) is the pharmacologically active metabolite of oxcarbazepine, a drug indicated for the treatment of partial seizures and bipolar disorders. | |||
T0008 | Phenytoin sodium | 5,5-Diphenylhydantoin sodium salt,Diphantoine,Dilantin sodium,Diphenylhydantoin Sodium | Virus Protease , Sodium Channel |
Phenytoin sodium (Diphantoine) is an inactive stabilizer for voltage-gated sodium channel . | |||
T2173 | Veratridine | Sodium Channel | |
Veratridine is a benzoate-cevane found in Veratrum and Schoenocaulon. It activates sodium channels to stay open longer than normal. | |||
T11990 | Meclofenamic acid | Meclofenamate | Others , Gap Junction Protein |
Meclofenamic acid (Meclofenamate) is a non-selective gap-junction blocker and a selective fat mass and obesity-associated (FTO) enzyme inhibitor. Meclofenamic acid has anti-inflammatory activities. | |||
T60010 | BTT-266 | Calcium Channel | |
BTT-266 is a blocker of voltage-gated calcium channel for pain management. | |||
T77711 | Calcium Channel antagonist 4 | Calcium Channel | |
Calcium Channel antagonist 4 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM). | |||
T77712 | Calcium Channel antagonist 3 | Calcium Channel | |
Calcium Channel antagonist 3 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM). | |||
T31716 | Etidocaine Hydrochloride | W-19053,Duranest,W19053,W 19053 | Sodium Channel |
Etidocaine Hydrochloride (W19053) is a long-acting anesthetic and a blocker of the voltage-gated sodium channel. | |||
T22675 | Co 102862 | V 102862 | Others , Sodium Channel |
Co 102862 is a voltage-gated sodium channel blocker. Co 102862 can be used for anticonvulsant studies. | |||
T9751 | Transfluthrin | Others | |
Transfluthrin is a volatile pyrethroid insecticide that targets insect voltage-gated sodium channels (VGSC). | |||
T12424 | PF-06305591 | PF-6305591 | Others |
PF-06305591 is an effective and selective blocker of voltage-gated sodium channel NaV1.8 (IC50 = 15 nM). | |||
T2523 | Rufinamide | CGP 33101,E 2080,RUF 331 | Sodium Channel |
Rufinamide (E 2080), a triazole derivative, is used as voltage-gated sodium channel blocker for the treatment of seizure disorders. | |||
T6571 | Lomerizine dihydrochloride | Terranas,Lomerizine 2HCl,Lomerizine hydrochloride,KB-2796 | Calcium Channel |
Lomerizine dihydrochloride (KB-2796) is an antagonist of L- and T-type voltage-gated calcium channels used to treat migraine. | |||
T23497 | UK 78282 hydrochloride | Potassium Channel | |
UK 78282 hydrochloride, a novel potent and selective Kv1.3 blocker.UK 78282 hydrochloride inhibits Kv1.3 voltage-gated potassium channels and suppresses human T cell activation. | |||
T12181 | NaV1.7 inhibitor-1 | Sodium Channel | |
NaV1.7 inhibitor-1, an efficacious inhibitor of voltage-gated sodium channel (NaV) 1.7 (IC50 of 0.6 nM for hNaV1.7). | |||
T7066 | Fosphenytoin disodium | Fosphenytoin sodium,ACC-9653 | Sodium Channel |
Fosphenytoin disodium (ACC-9653) is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker |