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Search Result

Search Results for " upar "

Targets

PARP Wnt/beta-catenin

16

Compounds

10

Natural Products

13

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T61932 Nesuparib JPI-547/OCN-201 PARP , Wnt/beta-catenin
Nesuparib (JPI-547/OCN-201) is a potent PARP inhibitor with inhibitory effects on PARP and TNKS1.Nesuparib has antitumor activity and can be used in the treatment of tumors, endocrine and metabolic disorders, genitourina...
T77566 (3aR,9aR)-Fluparoxan Adrenergic Receptor
(3aR,9aR)-Fluparoxan is a highly selective and potent adrenergic receptor α2B antagonist for the prevention, amelioration or treatment of neurodevelopmental disorders and neurodegenerative diseases.
T1827 Buparlisib BKM120,NVP-BKM120 Apoptosis , PI3K
Buparlisib (BKM120) is an orally bioavailable specific oral inhibitor of the pan-class I PI3K (IC50s: 52/166/116/nM for p110α, p110β, and p110δ).
T77565 Fluparoxan hydrochloride Adrenergic Receptor
Fluparoxan hydrochloride is a highly selective and potent α2-adrenoceptor antagonist for the prevention, amelioration or treatment of neurodevelopmental disorders and neurodegenerative diseases.
T77412 Lupartumab BAY 1112623 Others
Lupartumab (BAY 1112623) is an anti-LYPD3 (C4.4A) monoclonal antibody that can be used to synthesize antibody-active molecular couplers that can be used to study LYPD3-associated tumor diseases.
T4269 Buparvaquone Butalex,BW 720C Antibiotic , Parasite
Buparvaquone (BW 720C) is a hydroxynaphthoquinone antiprotozoal drug related to atovaquone and parvaquone.
T80918 Tuparstobart Incagn-02385
Tuparstobart (Incagn-02385) is an IgG1κ monoclonal antibody that targets the immune checkpoint receptor protein LAG-3, which is predominantly expressed on activated T cells, NK cells, B cells, and plasmacytoid dendritic ...
T27340 Fluparoxan HCl GR50360,GR 50360,Fluparoxan hydrochloride,GR-50360A,GR-50360
Fluparoxan is a potent α2-adrenergic receptor antagonist (pKB = 7.9) with excellent α2/α1 selectivity (2630 fold).
T70785 Mefuparib Free Base
Mefuparib Free Base is a potent, highly selective, competitive PARP1/2 inhibitor with IC50 of 3.2/1.9 nM, respectively. Mefuparib (CVL218), has been shown to have promising antiviral activity against the virus that cause...
T11992 Mefuparib hydrochloride MPH PARP
Mefuparib hydrochloride induces apoptosis and possesses prominent anticancer activity in vitro and in vivo. Mefuparib hydrochloride (MPH) is an orally active, substrate-competitive and selective PARP1/2 inhibitor with IC...
T16365 Buparlisib Hydrochloride NVP-BKM120 Hydrochloride,BKM120 Hydrochloride Others
Buparlisib Hydrochloride is an inhibitor of pan-class I PI3K (IC50: 52 nM/166 nM/116 nM/262 nM for p110α/p110β/p110δ/p110γ, respectively).
T68074 Fluparoxan
Fluparoxan is a highly selective and potent alpha 2-adrenoceptor antagonist.
TP2338L Cenupatide acetate Cenupatide acetate(1006388-38-0 Free base) Others
Cenupatide acetate is an urokinase plasminogen activator receptor (uPAR) inhibitor for treating disorders associated altered cell migration, such as cancer.
T11666 IPR-803 Serine/threonin kinase
IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity. IPR-803 binds directly to uPAR with a Ki of 0.2 μM.
T26629 Angstrom6 A-6,A 6 peptide,A6,A 6,A6 peptide,A-6 peptide PAI-1
Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascade and abrogates the downstream effects.Angstrom6 has antitumor a...
TP2338 Cenupatide UPARANT,Cenupatide trifluoroacetic acid salt,Ac-Arg-Aib-Arg-α(Me)Phe-NH2)
Cenupatide is a urokinase plasminogen activator receptor (uPAR) inhibitor. Cenupatide inhibits uPAR binding to the formyl peptide receptors (FPRs) can improve kidney lesions in a rat model of STZ-induced diabetes. Cenupa...
Cat No. Product Name Synonyms Targets
TN6762 (+)-Cuparene Others
(+)-Cuparene is a bioactive chemical.
TN3469 Aucuparin 2,6-dimethoxy-4-phenylphenol NADPH-oxidase
Aucuparin (2,6-dimethoxy-4-phenylphenol) is a plant antibiotic with anti-inflammatory activity. Aucuparin inhibited pulmonary fibrosis in mouse models induced by bleomycin (BLM). ABTS and FRAP showed clear scavenging act...
TN2693 2,3-Dihydro-12,13-dihydroxyeuparin Others
2,3-Dihydro-12,13-dihydroxyeuparin is a natural product for research related to life sciences. The catalog number is TN2693 and the CAS number is 135531-75-8.
T81653 Noraucuparin
Noraucuparin, a biphenyl-type phytoalexin with antifungal properties, can be isolated from the leaves of Sorbus pohuashanensis [1].
TN4258 Isocuparenal Others
Isocuparenal is a natural product for research related to life sciences. The catalog number is TN4258 and the CAS number is 16982-01-7.
TN1632 Euparin Antifection
Euparin exhibits a moderate antioxidant activity, it also exhibits antifungal activity against Trichophyton mentagrophytes. Euparin has antiviral activity, it exerts its effect during the early events of the replication ...
TN5160 Trans-2,3-Dihydro-3-ethoxyeuparin Others
trans-2,3-Dihydro-3-ethoxyeuparin is a natural product for research related to life sciences. The catalog number is TN5160 and the CAS number is 1015698-14-2.
TN2596 12-Hydroxy-2,3-dihydroeuparin Others
12-Hydroxy-2,3-dihydroeuparin is a natural product of Eupatorium, Asteraceae. The catalog number is TN2596 and the CAS number is 68776-42-1. 12-Hydroxy-2,3-dihydroeuparin can be used as a reference standard.
TN5161 Trans-2,3-Dihydro-3-hydroxyeuparin Others
trans-2,3-Dihydro-3-hydroxyeuparin is a natural product for research related to life sciences. The catalog number is TN5161 and the CAS number is 64185-57-5.
TN4036 Euparone Others
Euparone is a benzofuran from Ruscus aculeatus L..

Natural Products

(+)-Cuparene
TN6762
Synonym:
Target: Others
Aucuparin
TN3469
Synonym: 2,6-dimethoxy-4-phenylphenol
Target: NADPH-oxidase
2,3-Dihydro-12,13-dihydroxyeuparin
TN2693
Synonym:
Target: Others
Noraucuparin
T81653
Synonym:
Target:
Isocuparenal
TN4258
Synonym:
Target: Others
Euparin
TN1632
Synonym:
Target: Antifection
trans-2,3-Dihydro-3-ethoxyeuparin
TN5160
Synonym:
Target: Others
12-Hydroxy-2,3-dihydroeuparin
TN2596
Synonym:
Target: Others
trans-2,3-Dihydro-3-hydroxyeuparin
TN5161
Synonym:
Target: Others
Euparone
TN4036
Synonym:
Target: Others

Recombinant Proteins

Species：
Human (7)
Mouse (4)
Cynomolgus (1)
Rat (1)
Expression System：
HEK293 Cells (12)
E. coli (1)
Tag：
C-His-Avi (4)
C-6xHis (2)
C-His (2)
His (2)
C-hFc (1)
His, hFc (1)
N-6xHis (1)
Cat No. Product Name Species Expression System
TMPY-01257 uPAR/PLAUR Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
uPAR/PLAUR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.4 kDa and the accession number is P35456-1.
TMPY-02141 uPAR/PLAUR Protein, Human, Recombinant (His) Human HEK293 Cells
uPAR/PLAUR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.8 kDa and the accession number is Q03405-1.
TMPY-01017 uPAR/PLAUR Protein, Mouse, Recombinant (His & hFc) Mouse HEK293 Cells
uPAR/PLAUR Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 58 kDa and the accession number is P35456-1.
TMPK-01175 uPAR/PLAUR Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin...
TMPK-00228 uPAR/PLAUR Protein, Human, Recombinant (hFc) Human HEK293 Cells
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin...
TMPK-00216 uPAR/PLAUR Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293 Cells
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin...
TMPK-00227 uPAR/PLAUR Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin...
TMPK-00226 uPAR/PLAUR Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin...
TMPK-00215 uPAR/PLAUR isoform 1 Protein, Mouse, Recombinant (His & Avi) Mouse HEK293 Cells
The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasmin...
TMPH-03397 uPAR/PLAUR Protein, Rat, Recombinant (His) Rat E. coli
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. uPAR/PLAUR Protein,...
TMPK-01225 MRC2 Protein, Human, Recombinant (His) Human HEK293 Cells
MRC2 (Mannose Receptor C Type 2) is a constitutively recycling endocytic receptor belonging to the mannose receptor family, which has been found to be closely involved with cancer metastasis. MRC2 expresses an extracellu...
TMPJ-00541 CD177 Protein, Human, Recombinant (His) Human HEK293 Cells
CD177 is polymorphic and has at least two alleles: PRV1 and NB1. Human PRV1 is a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein that belongs to the uPAR/CD59/Ly6 family of receptors. PRV1 is express...
TMPJ-00709 LY6H Protein, Human, Recombinant (His) Human HEK293 Cells
Lymphocyte Antigen 6H (LY6H) is a novel member of the LY6 family of glycosylphosphatidylinositol-anchored cell surface glycoproteins. LY6H contains one UPAR/Ly6 domain. Human LY6H is synthesized as a 140 amino acid precu...
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