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Search Results for " uchl1 "

Targets

11

Compounds

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T10188 6RK73 Others
6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 µM). 6RK73 shows almost no inhibition of UCHL3 (IC50: 236 µM).
T6013 Z-VAD(OMe)-FMK Z-VAD-FMK,Z-Val-Ala-Asp(OMe)-FMK Caspase
Z-VAD(OMe)-FMK is a pan-caspase inhibitor with irreversible properties; Z-VAD(OMe)-FMK is also an inhibitor of ubiquitin C terminal hydrolase L1 (UCHL1), which is irreversibly modified by targeting the UCHL1 active site.
T7020 Z-VAD-FMK Z-VAD(OH)-FMK,Caspase Inhibitor VI,Z-VAD Caspase
Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does not inhibit UCHL1 activity, even at concentrations up to 440 μM.
T1924 LDN-57444 LDN57444 Apoptosis , DUB
LDN-57444 is a reversible, competitive proteasome Uch-L1 inhibitor(IC50=0.88 μM) .
T15729 LDN-91946 DUB
LDN-91946 is an effective and selective inhibitor of ubiquitin C-terminal hydrolase-L1 (UCH-L1) (Ki = 2.8 μM).
T37591 IMP-1710 DUB
IMP-1710 is a selective UCH-L1 inhibitor with an IC50 value of 38 nM in a fluorescence polarization assay.
T78425 GK16S
GK16S, a UCHL1 chemogenomic probe, serves as a complementary tool to GK13S for the investigation of UCHL1 function in cellular studies [1].
T70074 SB1-F-21
SB1-F-21 is an UCHL1 inhibitor.
T75182 GK13S
G13KS is a deubiquitinase UCHL1 ligand and inhibitor. G13KS inhibits recombinant and cellular UCHL1. G13KS reduces levels of monoubiquitin in human glioblastoma cells [1] .
T69539 8RK64
8RK64 is a covalent UCHL1 inhibitor ( IC 50 : 0.32 μM) .
T71586 Z-VAE(OMe)-fmk
Z-VAE(OMe)-fmk is a cell-permeable and irreversible UCHL1 inhibitor. The inhibitor approaches the active-site cleft from the opposite side of the crossover loop as compared to the direction of approach of ubiquitin's C-t...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02175 UCHL1 Protein, Mouse, Recombinant (His) Mouse E. coli
UCHL1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.2 kDa and the accession number is Q9R0P9.
TMPY-01547 UCHL1 Protein, Human, Recombinant (His) Human E. coli
UCHL1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 25.6 kDa and the accession number is P09936.
TMPY-02331 UCHL1 Protein, Rat, Recombinant (His) Rat E. coli
UCHL1 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.2 kDa and the accession number is Q00981.
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