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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10188 | 6RK73 | Others | |
6RK73 is a covalent irreversible and specific UCHL1 inhibitor (IC50: 0.23 µM). 6RK73 shows almost no inhibition of UCHL3 (IC50: 236 µM). | |||
T6013 | Z-VAD(OMe)-FMK | Z-VAD-FMK,Z-Val-Ala-Asp(OMe)-FMK | Caspase |
Z-VAD(OMe)-FMK is a pan-caspase inhibitor with irreversible properties; Z-VAD(OMe)-FMK is also an inhibitor of ubiquitin C terminal hydrolase L1 (UCHL1), which is irreversibly modified by targeting the UCHL1 active site. | |||
T7020 | Z-VAD-FMK | Z-VAD(OH)-FMK,Caspase Inhibitor VI,Z-VAD | Caspase |
Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does not inhibit UCHL1 activity, even at concentrations up to 440 μM. | |||
T1924 | LDN-57444 | LDN57444 | Apoptosis , DUB |
LDN-57444 is a reversible, competitive proteasome Uch-L1 inhibitor(IC50=0.88 μM) . | |||
T15729 | LDN-91946 | DUB | |
LDN-91946 is an effective and selective inhibitor of ubiquitin C-terminal hydrolase-L1 (UCH-L1) (Ki = 2.8 μM). | |||
T37591 | IMP-1710 | DUB | |
IMP-1710 is a selective UCH-L1 inhibitor with an IC50 value of 38 nM in a fluorescence polarization assay. | |||
T78425 | GK16S | ||
GK16S, a UCHL1 chemogenomic probe, serves as a complementary tool to GK13S for the investigation of UCHL1 function in cellular studies [1]. | |||
T70074 | SB1-F-21 | ||
SB1-F-21 is an UCHL1 inhibitor. | |||
T75182 | GK13S | ||
G13KS is a deubiquitinase UCHL1 ligand and inhibitor. G13KS inhibits recombinant and cellular UCHL1. G13KS reduces levels of monoubiquitin in human glioblastoma cells [1] . | |||
T69539 | 8RK64 | ||
8RK64 is a covalent UCHL1 inhibitor ( IC 50 : 0.32 μM) . | |||
T71586 | Z-VAE(OMe)-fmk | ||
Z-VAE(OMe)-fmk is a cell-permeable and irreversible UCHL1 inhibitor. The inhibitor approaches the active-site cleft from the opposite side of the crossover loop as compared to the direction of approach of ubiquitin's C-t... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02175 | UCHL1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
UCHL1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.2 kDa and the accession number is Q9R0P9. | |||
TMPY-01547 | UCHL1 Protein, Human, Recombinant (His) | Human | E. coli |
UCHL1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 25.6 kDa and the accession number is P09936. | |||
TMPY-02331 | UCHL1 Protein, Rat, Recombinant (His) | Rat | E. coli |
UCHL1 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 26.2 kDa and the accession number is Q00981. |