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Search Results for " tpx "

Targets

5

Compounds

4

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T35384 TPX-0046 c-RET , Src
TPX-0046 is a RET inhibitor designed to overcome resistance to Selpercatinib and Pralsetinib.
T67779 Compound TPX-0046 c-RET
Compound TPX-0046 is an inhibitor of RET. Compound TPX-0046 can inhibit the RET autophosphorylation. Compound TPX-0046 can be used for the research of cancer.
T4071 Repotrectinib TPX-0005,TPX 0005,TPX0005 Trk receptor , ROS , Src , ALK , ROS Kinase
Repotrectinib (TPX-0005) is a potent ALK/ROS1/TRK inhibitor, with IC50 of 1.01 nM, 5.3 nM, 1.08 nM and 1.26 nM for WT ALK, SRC, ALK L1196M and ALK G1202R, respectively.
T9414 TPX-0131
TPX-0131 is a potent, selective, CNS-penetrant and orally active inhibitor of wild-type ALK ( IC 50 of 1.4 nM) and is potent against ALK-resistant mutation, e.g. G1202R ( IC 50 of 0.3 nM), L1196M ( IC 50 of 0.3 nM). TPX-...
T71741 PPK-188
PPK-188, also known as CFT, is a novel selective covalent inhibitor of tryparedoxin (tpx), efficiently killing live african trypansosomes

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-02779 Thyroid peroxidase Protein, Human, Recombinant (S257A & P725T, His) Human Baculovirus Insect Cells
Thyroid peroxidase is a membrane-bound glycoprotein which belongs to the peroxidase family, XPO subfamily. It contains 1 EGF-like domain and 1 Sushi (CCP/SCR) domain. Thyroid Peroxidase represents one of the main autoant...
TMPY-05169 Peroxiredoxin 2 Protein, Mouse, Recombinant (His) Mouse Baculovirus Insect Cells
Peroxiredoxin 2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 24.1 kDa and the accession number is Q61171.
TMPJ-00933 PRDX5 Protein, Human, Recombinant (His) Human HEK293 Cells
Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Perox...
TMPY-02200 Peroxiredoxin 2 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Peroxiredoxin 2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 24 kDa and the accession number is P32119.
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