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Search Results for " tgfβ1 "

Targets

11

Compounds

5

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T75005 TGFβ1-IN-3 Others
TGFβ1-IN-3 is a diarylhydrazone derivative with inhibitory effects on fibroblast activation and proliferation.TGFβ1-IN-3 is a candidate compound for the treatment of idiopathic pulmonary fibrosis (IPF).
T75004 TGFβ1-IN-2 Others
TGFβ1-IN-2, a derivative of diarylacylhydrazones, effectively inhibits fibroblast activation and proliferation and holds potential for idiopathic pulmonary fibrosis (IPF) research [1].
T61389 TGFβ1-IN-1 TGF-beta/Smad
TGFβ1-IN-1 is an orally active TGF-β1 inhibitor that inhibits the production of TGF-β1-induced fibrotic markers (α-SMA and fibronectin) and can be used for the study of cancer and autoimmune diseases.
T7425 RU-301 TAM Receptor
RU-301 is a novel pan-tam inhibitor
T76681 Fresolimumab GC1008 TGF-beta/Smad
Fresolimumab (GC1008) is a specific human anti-transforming growth factor β monoclonal antibody that binds to the active forms of human TGFβ1, TGFβ2, and TGFβ3 and can be used to study focal segmental glomerulosclerosis ...
T11052L Disitertide acetate P144 acetate,Disitertide acetate(272105-42-7 Free base) TGF-beta/Smad
Disitertide acetate (P144 acetate) is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide acetate is also a PI3K inhibitor and an ...
T77067 Livmoniplimab
Livmoniplimab (ABBV-151; ARGX-115), a potent humanized monoclonal antibody targeting LRRC32 (GARP)/TGFβ1, inhibits LRRC32-mediated activation of latent TGFβ1. This compound shows promise for cancer research [1].
T76819 Metelimumab
Metelimumab (CAT-192), a human IgG4 monoclonal antibody, selectively neutralizes TGFβ1 [1].
T81931 Linavonkibart
Linavonkibart (SRK 181) is a fully human antibody with high affinity for latent TGFβ1, selectively binding and inhibiting its activation. This compound is significant in the context of cancer [1].
T75717 Disitertide diammonium
Disitertide (P144) diammonium, a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor, is specifically engineered to prevent its receptor interaction. Additionally, it serves as a PI3K inhibitor and induces apop...
T75716 Disitertide TFA
Disitertide (P144) TFA is a peptide-based inhibitor of transforming growth factor-beta 1 (TGF-β1), specifically engineered to prevent its interaction with the receptor. Additionally, it functions as a PI3K inhibitor and ...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00500 Latent TGF beta 1 Protein, Mouse, Recombinant (His) Mouse HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-05313 Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated Mouse HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPJ-00250 LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated Human Human Cells
Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFβ gene product. Extracellular activ...
TMPY-03861 Amelotin Protein, Human, Recombinant (mFc) Human HEK293
Amelotin (AMTN) is a tooth enamel protein which is expressed in maturation-stage ameloblasts and also in the internal basal lamina of junctional epithelium, a unique epithelial structure attached to the tooth surface whi...
TMPJ-00771 TGF beta 1 Protein, Mouse/Rat, Recombinant Mouse,Rat Human Cells
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differen...
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