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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T75005 | TGFβ1-IN-3 | Others | |
TGFβ1-IN-3 is a diarylhydrazone derivative with inhibitory effects on fibroblast activation and proliferation.TGFβ1-IN-3 is a candidate compound for the treatment of idiopathic pulmonary fibrosis (IPF). | |||
T75004 | TGFβ1-IN-2 | Others | |
TGFβ1-IN-2, a derivative of diarylacylhydrazones, effectively inhibits fibroblast activation and proliferation and holds potential for idiopathic pulmonary fibrosis (IPF) research [1]. | |||
T61389 | TGFβ1-IN-1 | TGF-beta/Smad | |
TGFβ1-IN-1 is an orally active TGF-β1 inhibitor that inhibits the production of TGF-β1-induced fibrotic markers (α-SMA and fibronectin) and can be used for the study of cancer and autoimmune diseases. | |||
T7425 | RU-301 | TAM Receptor | |
RU-301 is a novel pan-tam inhibitor | |||
T76681 | Fresolimumab | GC1008 | TGF-beta/Smad |
Fresolimumab (GC1008) is a specific human anti-transforming growth factor β monoclonal antibody that binds to the active forms of human TGFβ1, TGFβ2, and TGFβ3 and can be used to study focal segmental glomerulosclerosis ... | |||
T11052L | Disitertide acetate | P144 acetate,Disitertide acetate(272105-42-7 Free base) | TGF-beta/Smad |
Disitertide acetate (P144 acetate) is a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor specifically designed to block the interaction with its receptor. Disitertide acetate is also a PI3K inhibitor and an ... | |||
T77067 | Livmoniplimab | ||
Livmoniplimab (ABBV-151; ARGX-115), a potent humanized monoclonal antibody targeting LRRC32 (GARP)/TGFβ1, inhibits LRRC32-mediated activation of latent TGFβ1. This compound shows promise for cancer research [1]. | |||
T76819 | Metelimumab | ||
Metelimumab (CAT-192), a human IgG4 monoclonal antibody, selectively neutralizes TGFβ1 [1]. | |||
T81931 | Linavonkibart | ||
Linavonkibart (SRK 181) is a fully human antibody with high affinity for latent TGFβ1, selectively binding and inhibiting its activation. This compound is significant in the context of cancer [1]. | |||
T75717 | Disitertide diammonium | ||
Disitertide (P144) diammonium, a peptidic transforming growth factor-beta 1 (TGF-β1) inhibitor, is specifically engineered to prevent its receptor interaction. Additionally, it serves as a PI3K inhibitor and induces apop... | |||
T75716 | Disitertide TFA | ||
Disitertide (P144) TFA is a peptide-based inhibitor of transforming growth factor-beta 1 (TGF-β1), specifically engineered to prevent its interaction with the receptor. Additionally, it functions as a PI3K inhibitor and ... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00500 | Latent TGF beta 1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d... | |||
TMPY-05313 | Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated | Mouse | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d... | |||
TMPJ-00250 | LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated | Human | Human Cells |
Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFβ gene product. Extracellular activ... | |||
TMPY-03861 | Amelotin Protein, Human, Recombinant (mFc) | Human | HEK293 |
Amelotin (AMTN) is a tooth enamel protein which is expressed in maturation-stage ameloblasts and also in the internal basal lamina of junctional epithelium, a unique epithelial structure attached to the tooth surface whi... | |||
TMPJ-00771 | TGF beta 1 Protein, Mouse/Rat, Recombinant | Mouse,Rat | Human Cells |
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differen... |