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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0374L | Sunitinib | SU 11248 | Apoptosis , Mitophagy , VEGFR , FLT , IRE1 , PDGFR , c-Kit , Autophagy |
Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase (RTK) inhibitor that inhibits VEGFR2 and PDGFRβ (IC50=80/2 nM). Sunitinib has antitumor activity and can be used for the treatment of kidney cancer and ga... | |||
T0374 | Sunitinib Malate | Sutent,SU 11248 (Malate),SU 11248,Sunitinib | Apoptosis , Mitophagy , VEGFR , FLT , IRE1 , PDGFR , c-Kit , Autophagy |
Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor. It blocks the tyrosine kinase activities of VEGFR2, PDGFRβ (IC50: 80/2 nM), and c-kit. |