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Search Results for " ssr "

20

Compounds

Cat No. Product Name Synonyms Targets
T84293 SSR 180
T28855 SSR126768A SSR-126768A,SSR 126768A Oxytocin Receptor
SSR126768A is a novel and selective, orally active and potent oxytocin (OT) receptor antagonist with inhibitory effects on uterine contractions for the prevention of preterm labor.
T6082 SSR128129E SSR FGFR
SSR128129E (SSR) is an allosteric and orally-active FGFR1 inhibitor (IC50: 1.9 μM), but not affecting other related RTKs.
T31095 Crinecerfont SSR125543,SSR 125543,SSR-125543,SSR125543A,SSR 125543A,SSR-125543A CRFR
Crinecerfont (SSR-125543) is a selective antagonist of corticotropin-releasing factor 1 receptor (CRF1) and can be used in studies about Classic congenital adrenal hyperplasia.
T69140 Burapitant SSR 240600 Neurokinin receptor
Burapitant (SSR 240600) is a novel non-peptide tachykinin neurokinin 1 (NK) receptor antagonist with anti-coke oven and antidepressant activity.
T28857 SSR-182289A (Free) SSR182289,SSR-182289A,SSR-182289,SSR 182289A,SSR182289A,SSR 182289
SSR-182289A (Free) is a thrombin inhibitor.
T28856 SSR180711 hydrochloride SSR-180711A HCl,SSR-180711C HCl,SR-180711 HCl AChR
SSR180711 hydrochloride (SSR-180711A HCl) is a selective Alpha7 nicotinic acetylcholine partial agonist for the study of neurodegenerative and cognitive disorders.
T21989 SSR 69071
SSR69071 is a potent, orally active, and selective inhibitor of neutrophil elastase. SSR69071 displays a higher affinity for human elastase (Ki =0.0168 nM) than for rat (Ki =3 nM), mouse (Ki =1.8 nM), and rabbit (Ki = 58...
T13002 SSR-241586 Others
SSR-241586 is a neurokinin receptors antagonist,and is shown to be active in the treatment of depression, schizophrenia, urinary trouble, emesis, and irritable bowel syndrome (IBS).
T23395 SSR 146977 hydrochloride Others
NK3 receptor antagonist
T5048 SSR240612 Bradykinin Receptor
SSR240612 is a potent, and orally active specific non-peptide bradykinin B1 receptor antagonist (Kis = 0.48-0.73 and 358-481 nM for B1 and B2 receptors, respectively).
T28858 SSR504734 SSR-504734,SSR 504734
SSR504734 is a novel potent glycine transporter 1 (GlyT1) inhibitor.
T40398 Crinecerfont hydrochloride SSR-125543A,SSR-125543 hydrochloride
Crinecerfont hydrochloride (SSR-125543) is a highly potent, orally active, non-peptide antagonist of the CRF1 receptor. It has demonstrated efficacy in the context of Classic congenital adrenal hyperplasia (CAH) research...
T13003 SSR128129E free acid SSR free acid FGFR
SSR128129E free acid is an orally available and allosteric inhibitor of FGFR(IC50 of 1.9 μM for FGFR1).
T15276 Ferroquine SSR97193,Ferrochloroquine Others
Ferroquine (Ferrochloroquine) is a ferrocenyl analogue of Chloroquine with antimalarial activity. Ferroquine induces oxidative stress and the subsequent destruction of the membrane, resulting in parasiticidal effect on P...
T28153 Nelivaptan SSR149415,SR 149415,SR-149415 Vasopressin Receptor
Nelivaptan (SR 149415) is a vasopressin V1b receptor antagonist.
T40775 SSR411298 SSR411298
SSR411298 is a reversible, orally active compound that selectively inhibits fatty acid amide hydrolase (FAAH). Its potential lies in the field of post-traumatic stress disorder (PTSD) research.
T11006 Desmethyl ferroquine SSR97213 Others
Desmethyl ferroquine is the active and major metabolite of Ferroquine.Desmethyl ferroquine shows significant activity against Chloroquine-susceptible and resistant P. falciparum strains. Ferroquine is an antimalarial.
T90597 SSR504734 HCl
SSR504734 is an orally active, selective and reversible inhibitor of human, rat, and mouse GlyT1 ( IC 50 =18, 15, and 38 nM, respectively). SSR504734 exhibits activity in schizophrenia, anxiety and depression models [1].
T60126 4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine Others , CRFR
4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine is an enantiomeric counterpart of SSR-125543. SSR-125543 is a potent CRF-R1 antagoni...
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