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Search Results for " sh3 "

7

Compounds

Cat No. Product Name Synonyms Targets
T9039 HIV-1 Nef-IN-1 HIV Protease
HIV-1 Nef-IN-1 is an inhibitor of HIV-1 Nef protein. It efficiently competes for Nef-SH3Hck interactions(Kd : 6.7 μM).
T74284 SH379
SH379, a potent and orally active derivative of 2-methylpyrimidine-fused tricyclic diterpene, serves as an effective agent against late-onset hypogonadism. It significantly enhances the expression of StAR and 3β-HSD, cru...
T38387 Compound C108 GTPase
Compound C108 is an inhibitor of GTPase-activating protein SH3 domain-binding protein 2 (G3BP2). Compound C108 can be used in studies about breast tumors and esophageal squamous cell carcinoma.
T4403 AX-024 hydrochloride AX-024 HCl IL Receptor , TNF , COX , IFNAR , Interleukin
AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
T37422 Ras Inhibitory Peptide
Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to t...
T75841 Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA
Ac-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH TFA (compound 1) serves as a high-affinity pentapeptide that binds to the src SH2 domain with an IC 50 value of approximately 1 µM. Additionally, it acts as an inhibitor of src SH3-SH2: p...
T61071 AX-024
AX-024 is a novel chemical compound that acts as an orally available inhibitor of the TCR-Nck interaction. Its primary mechanism of action is the selective inhibition of T cell activation triggered by TCR stimulation. Wi...
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