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Search Results for " sapk2a "

Targets

3

Compounds

1

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T1764 Adezmapimod PB 203580,RWJ 64809,SB203580 Mitophagy , p38 MAPK , Autophagy
Adezmapimod (SB 203580) is a p38 MAPK inhibitor (IC50=0.3-0.5 μM) that is selective and ATP-competitive. Adezmapimod possesses autophagy and mitochondrial autophagy activating activity. Adezmapimod displays more than 100...
T6458 CYC-116 VEGFR , FLT , CDK , S6 Kinase , Aurora Kinase
CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active against PKA, Akt/PKB, PKC, no effect on GSK-3α/β, CK2, Plk1 ...
T21675 SB 203580 hydrochloride
Adezmapimod (SB 203580) hydrochloride is a selective ATP-competitive inhibitor of p38 MAPK, displaying IC50 values of 50 nM for SAPK2a/p38 and 500 nM for SAPK2b/p38β2. This compound also inhibits LCK, GSK3β, and PKBα, al...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-04260 P38 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
MAPK14 contains 1 protein kinase domain and belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as prol...
TargetMol