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Search Results for " ruxolitinib "

8

Compounds

Cat No. Product Name Synonyms Targets
T1829 Ruxolitinib INCB018424,(R)-Ruxolitinib Apoptosis , Mitophagy , Tyrosine Kinases , JAK , Autophagy
Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective. Rixolitinib exhibits antitumor activity and induces autophagy and apoptosis.
T6156 Ruxolitinib (S enantiomer) S-Ruxolitinib,Ruxolitinib S enantiomer,INCB018424,INCB18424 Tyrosine Kinases , JAK
Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.
T3043 Ruxolitinib phosphate INC424,INCB018424,INC 424 phosphate,Ruxolitinib (INCB-18424) phosphate,INCB018424 phosphate Mitophagy , JAK , Autophagy
Ruxolitinib phosphate (INCB018424)(INCB018424 phosphate) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3.
T3066 S-Ruxolitinib JAK
S-Ruxolitinib can be used in related research in the field of life sciences. Its product number is T3066 and CAS number is 1160597-27-2.
T61988 Ruxolitinib sulfate
Ruxolitinib sulfate (INCB018424 sulfate) is a potent, selective JAK1/2 inhibitor with IC 50 s of 3.3 nM/2.8 nM. Ruxolitinib sulfate shows > 130-fold selectivity for JAK1/2 versus JAK3.
T2476 INCB032304 4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)-methyl)-7H-pyrrolo[2,3-d]pyrimidine Others
INCB032304 is an important pharmaceutical intermediate. It can be used in the preparation of Ruxolitinib phosphate (I008849), a janus kinase inhibitor, and in the preparation of Barretinib.
T74994 SJ988497
SJ988497 is a PROTAC JAK2 degrader that effectively inhibits proliferation in CRLF2-rearranged (CRLF2r) cells and facilitates the degradation of the CRBN neosubstrate GSPT1. Composed of a Ruxolitinib derivative, a linker...
T38158 StA-IFN-1
StA-IFN-1 is an inhibitor of the interferon (IFN) induction pathway with an IC50 value of 4.1 μM in a GFP reporter assay for IFN induction similar to TPCA-1 , which specifically inhibits the IKKβ component of the IFN ind...
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