Home Tools
Log in
Cart

Search Result

Search Results for " ro4 "

11

Compounds

Cat No. Product Name Synonyms Targets
T2087 AF-353 Ro-4 P2X Receptor
AF-353 (Ro-4), an effective and orally bioavailable antagonist of the P2X3/P2X2/3 receptor, inhibits human and rat P2X3 (pIC50= 8.0).
T22416 RO495 CS-2667 Tyrosine Kinases , JAK
RO495 (CS-2667), a potent inhibitor of TYK2, inhibits TYK2 with IC50 of 1.5nM as tested in cell-based pharmacological assays
T5412 RO4987655 CH4987655,RG7167 MEK
RO4987655 (RG7167) is an orally active and highly selective MEK inhibitor (IC50: 5.2 nM for MEK1/MEK2).
T6274 RO4929097 RG-4733 Beta Amyloid , Gamma-secretase
RO4929097 (RG-4733), a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).
T83495 [D-Pro4,D-Trp7,9] Substance P (4-11)
[D-Pro4,D-Trp7,9] Substance P (4-11) acts as a potent antagonist to Substance P, significantly reducing plasma aldosterone (ALDO) concentrations[1].
T83496 [D-Pro4,D-Trp7,9,10] Substance P (4-11)
[D-Pro4,D-Trp7,9,10] Substance P (4-11) serves as a potent antagonist of the tachykinin family of neuropeptides [1].
T76406 [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11)
[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) is a potent neurokinin NK1 antagonist that effectively inhibits the actions of gold-protein-substance P (GPSP) and substance P (SP), demonstrating its efficacy in neutralizing t...
T28600 Ro4491533 Ro 4491533,Ro-4491533
Ro4491533 is a potent and selective negative allosteric modulator for group II of the metabotropic glutamate receptors (mGluR2/3).
T28601 RO4988546 RO-4988546,RO 4988546
RO4988546 is a potent negative allosteric modulator of mGlu₂/₃.
T68623 RO4583298
RO4583298 is a highly potent dual NK1/NK3 receptor antagonist with in vivo activity.
T68459 RO4927350
RO4927350 is a potent and highly selective non-ATP-competitive MEK1/2 inhibitor. RO4927350 selectively blocks the MAPK pathway signaling both in vitro and in vivo, which results in significant antitumor efficacy in a bro...
TargetMol