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Home > Neuroscience > Gamma-secretase > RO4929097

RO4929097

Catalog No. T6274    CAS 847925-91-1    Synonyms: RG-4733

RO4929097, a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).

Pack Size Availability Price/USD Quantity
2 mg In stock 64.00
5 mg In stock 103.00
10 mg In stock 186.00
25 mg In stock 364.00
50 mg In stock 560.00
1 mL * 10 mM (in DMSO) In stock 103.00
Bulk Size: Please Quote for Discount Please Quote for Bulk Size
Biological Activity:

Product Description:

RO4929097, a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).

Receptor:

Aβ40; γ secretase; γ secretase(ICN); Notch;

Chemical Information:
Molecular Weight 469.40
Formula C22H20F5N3O3
CAS Number 847925-91-1
Solubility

DMSO: 86 mg/mL, 183.2 mM

Ethanol: 13 mg/mL, 27.7 mM

Water: Insoluble

( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage store at -80°C
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.