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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T21652 | RN-1 dihydrochloride | Histone Demethylase , MAO | |
RN-1 dihydrochloride is an effective and selective irreversible inhibitor of lysine-specific demethylase 1 (LSD1, IC50 = 70 nM). | |||
T12711 | Retro-2 cycl | RN 1-001 | Virus Protease |
Retro-2 cycl is a dihydroquinazolinone (DHQZ) retrograde trafficking inhibitor. Retro-2 cycl (RN 1-001) inhibits JCPyV and HPV16 pseudovirus(IC50s of 54 μM and 160 μM, respectively),with antiviral agent. | |||
T16764 | RN-18 | HIV Protease | |
RN-18 is an inhibitor of HIV-1 viral infectivity factor (IC50: 6 μM in nonpermissive H9 cells). | |||
T12818 | S119-8 | Influenza Virus | |
RN-18 antagonizes Vif function and inhibits HIV-1 replication only in the presence of A3G. RN-18 increases cellular A3G levels in a Vif-dependent manner and increases A3G incorporation into virions without inhibiting gen... | |||
T6776 | BAY 61-3606 dihydrochloride | BAY 61-3606,BAY-61-3606 dihydrochloride | Apoptosis , Syk |
BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM). | |||
T4263 | BAY 61-3606 | Syk inhibitor IV | Apoptosis , Syk |
BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting no inhibitory effect against Btk, Fyn, Itk, Lyn, and Src. | |||
T37321 | RN-9893 (hydrochloride) | ||
RN-9893 is an antagonist of transient receptor potential vanilloid 4 (TRPV4; IC50s = 0.42 and 0.66 μM, respectively, for the human and rat receptors).1 It is selective for TRPV4 over TRPV1, TRPV3, and TRPM8 (IC50s = 10, ... | |||
T78282 | Tanezumab | RN-624,PF 4383119 | |
Tanezumab (RN-624) is a high-affinity, specific humanized anti-NGF monoclonal antibody (mAb) that inhibits nerve growth factor (NGF) from binding to its p75 and TrkA receptors in the peripheral nervous system. It is util... |