pyr — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6629	PYR-41	PYR41,PYR 41	Apoptosis , E1/E2/E3 Enzyme
	PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2.		Apoptosis , E1/E2/E3 Enzyme
T15665	KJ Pyr 9		c-Myc , Autophagy
	KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).		c-Myc , Autophagy
T21349	PYR-8750	PYR 8750
	PYR-8750 is an intermediate used for chemical synthesis of a number of biologically important molecules, including bile pigments, photosensitizers, porphyrins, anticancer drugs.
T21348	PYR-0503
	PYR-0503 is an intermediate used for chemical synthesis of a number of biologically important molecules, including bile pigments, photosensitizers, porphyrins, anticancer drugs.
T21347	PYR-9588	PYR9588
	PYR-9588 is an intermediate used for chemical synthesis of a number of biologically important molecules, including bile pigments, photosensitizers, porphyrins, anticancer drugs.
T81341	Pyr-Gly
	Pyr-Gly is an inhibitory peptide that suppresses the proliferation of retinal pigment epithelium (RPE) cells and fibroblasts [1].
T16687	Pyr3		TRP/TRPV Channel
	Pyr3 is a selective transient receptor potential canonical channel 3 inhibitor. Pyr3 inhibits TRPC3-mediated Ca2+ influx in a dose-dependent manner(IC50 = 700 nM).		TRP/TRPV Channel
T81914	L-Pyroglutamic acid β-naphthylamide	PYR
	L-Pyroglutamic acid β-naphthylamide (PYR) is a derivative of glutamic acid.
T16686	Pyr10		TRP/TRPV Channel
	Pyr10 is a pyrazole derivative and a selective TRP cation 3 inhibitor. Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1)/Orai1 channels. Pyr10 inhibits...		TRP/TRPV Channel
T78036	Pyr-Arg-Thr-Lys-Arg-AMC TFA
	Pyr-Arg-Thr-Lys-Arg-AMC TFA, an AMC-tagged decapeptide, is selectively cleaved by proteases including trypsin and thrombin. This AMC peptide serves as a substrate for measuring protease activity and assessing the efficac...
T34206	Pyroglutaminyl-seryl-leucinamide	Thyrotropin releasing hormone-AN,Trh-AN,Pyr-ser-leu-NH2
	Pyroglutaminyl-seryl-leucinamide is a bioactive chemical.
T16688	Pyr6	N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide	TRP/TRPV Channel
	Pyr6 (N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide) is a selective TRPC3 inhibitor with IC50 of 0.49 uM(Ca2+ influx inhibition in thapsigargin depleted native RBL-2H3 cells).Pyr6 ...		TRP/TRPV Channel
TP1260	[Pyr1]-Apelin-13	[pGlu1]-Apelin-13	Apelin receptor
	[Pyr1]-Apelin-13 ([pGlu1]-Apelin-13) is a potent and selective endogenous Apelin receptor (APJ) agonist.		Apelin receptor
TP2309	Neurotensin TFA	NEUROTENSIN TFA,Neurotensin TFA (39379-15-2 free base)	Others
	Neurotensin TFA (39379-15-2 free base) is an endogenous 13 amino acid neuropeptide with profound opioid-independent analgesic effects. It behaves as a neurotransmitter in the brain, as a hormone in the gut, and also as a...		Others
T64321	Octyl-beta-D-glucopyranoside	Octyl glucoside,11β-HSD1-IN-11	Others
	Octyl-beta-D-glucopyranoside (11β-HSD1-IN-11) is a non-ionic detergent, it can be widely used in the research of biotechnical, biochemical applications, solubilization and crystallization of membrane proteins.		Others
TN7029	(2S)-1-O-p-coumaroyl-2-O-acetyl-3-O-β-D-glucopyranosylglycerol		Others
	(2S)-1-O-p-coumaroyl-2-O-acetyl-3-O-β-D-glucopyranosylglycerol is a useful research compound for many research applications, including the fields of chemistry and life sciences, among others.		Others
T4864	Methyl β-D-Galactopyranoside	Methyl-β-D-galactopyranoside	Others , Endogenous Metabolite
	Within the cell, Methyl β-D-Galactopyranoside (Methyl-β-D-galactopyranoside) is primarily located in the cytoplasm. Outside of the human body, Methyl β-D-Galactopyranoside can be found in cereals and cereal products.		Others , Endogenous Metabolite
T17326	2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide	2-3-4-6-tetra-o-acetyl-alpha-galactosylpyranosyl-bromide	Others , PROTAC Linker
	2,3,4,6-Tetra-o-acetyl-alpha-galactosylpyranosyl bromide (2-3-4-6-tetra-o-acetyl-alpha-galactosylpyranosyl-bromide) is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis.		Others , PROTAC Linker
T50028	6-fluoro-3-(4-1,2,5,6-tetrahydropyridyl)indole	6-fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole	Others
	6-fluoro-3-(4-1,2,5,6-tetrahydropyridyl)indole (6-fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole) is an indole derivative with potential anticancer activity and a potential lead compound for the development of new d...		Others
T5251	Phenylpyruvic acid	2-Oxo-3-phenylpropanoic acid,3-Phenylpyruvic acid	Others , Endogenous Metabolite
	Phenylpyruvic acid (3-Phenylpyruvic acid) is a keto-acid that is an intermediate or catabolic byproduct of phenylalanine metabolism. It has a slight honey-like odor. Levels of phenylpyruvate are normally very low in bloo...		Others , Endogenous Metabolite