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Search Results for " psma "

27

Compounds

1

Natural Products

9

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T28466 PSMA-11 HBED-CC-PSMA,Psma-hbed-CC,PSMA11
PSMA-11 (HBED-CC-PSMA) detects prostate cancer recurrence and metastasis by binding to the extracellular structural domain of prostate-specific membrane antigen (PSMA).PSMA-11 is often used as a tracer of PSMA-expressing...
T40326 PSMA–DA1 PSMA–DA1
PSMA–DA1 may be a useful PSMA-targeting radiotheranostic agent.
T12573 Vipivotide tetraxetan PSMA-617 Others
Vipivotide tetraxetan (PSMA-617) is a high potent inhibitor of prostate-specific membrane antigen (PSMA)(Ki of 0.37 nM).
T39831 PSMA-ALB-56
PSMA-ALB-56 is a PSMA-targeting radioactive ligand with antitumor activity designed by binding glutamic urea PSMA binding entities, DOTA chelating agents, and albumin binators based on 4-(p-iodophenyl)- fragment or p(tol...
T69924 PSMA-1007
PSMA-1007 is a novel Glu-Ureido-type prostate-specific membrane antigen (PSMA) inhibitor.
T78927 PSMA-IN-3
PSMA-IN-3 (compound 17) is a novel, high-affinity inhibitor of Prostate-Specific Membrane Antigen (PSMA) with an inhibitory concentration (IC50) of 13 nM, showing potential for the development of an 18F-labeled radioliga...
T78153 PSMA I&T Others
PSMA I&T, a potent inhibitor of prostate-specific membrane antigen (PSMA), facilitates SPECT/CT imaging and radionuclide research in prostate cancer (PCa) [1].
T78412 Biotin-NH-PSMA-617
Biotin-NH-PSMA-617 is a biotinylated derivative of the small molecule PSMA-617, designed to target the prostate-specific membrane antigen (PSMA) that is prominently expressed on prostate tumor cells [1].
T17233 Vipivotide tetraxetan Linker PSMA-617 Linker Others
Vipivotide tetraxetan Linker (PSMA-617 Linker) is a noncleavable peptide linker utilized in the synthesis of Vipivotide tetraxetan (PSMA-617), a ligand instrumental in producing 177Lu-PSMA-617. This radioactive molecule ...
T81361 PSMA-Val-Cit-PAB-MMAE
PSMA-Val-Cit-PAB-MMAE is a novel PSMA-targeted small-molecule conjugate leveraging monomethyl auristatin E (MMAE) for prostate cancer chemotherapy.
T28467 PSMA617-TCMC TFA PSMA617-TCMC TFA salt,PSMA617-analog, PSMA617-derivative with TCMC,PSMA-617-TCMC
PSMA617-TCMC is a derivative of PSMA-617 with structure modification, in which the caroboxy groups in DOTA ring is replaced by TCMC macrocycle. PSMA-617 is a ligand used to make 177Lu-PSMA-617, which is a radioactive mol...
T69923 Brigimadlin BI 907828
Brigimadlin (BI 907828), an E3 ubiquitin-protein ligase MDM-2 inhibitor, functions as an antineoplastic agent.
T31224 Piflufolastat DCFPYL Epigenetic Reader Domain
Piflufolastat (DCFPYL) is a PET imaging agent for prostate cancer PSMA. It is a fluorinated prostate-specific membrane antigen (PSMA) preparation. Piflufolastat can be used to prepare piflufolastat F 18 (DCFPyL F-18).
T8925L Glu-urea-Lys TFA(1025796-69-3 free base) Others
Glu-urea-Lys TFA (1025796-69-3 free base) is a PSMA inhibitor.
T11122 DUPA(OtBu)-OH Others
DUPA(OtBu)-OH is a DUPA precursor. DUPA is used as the targeting moiety to actively deliver Docetaxel (DTX) for treatment of Prostate-Specific Membrane Antigen (PSMA) expressing prostate cancer. PSMA has a high affinity ...
T8925 Glu-urea-Lys
Glu-urea-Lys is a molecular scaffold that targets PSMA and can be used as a prostate cancer imaging agent to study prostate-specific membrane antigens.
T9280 CS-0047390 (S)-Di-tert-butyl 2-(3-((S)-6-amino-1-(tert-butoxy)-1-oxohexan-2-yl)ureido)pentanedioate Others
CS-0047390 ((S)-Di-tert-butyl 2-(3-((S)-6-amino-1-(tert-butoxy)-1-oxohexan-2-yl)ureido)pentanedioate), also known as tert-Butyl-DCL, is a PSMA inhibitor and a radiopaque peptide reagent.
T19301 DUPA N,N''-Carbonylbis[L-glutamic acid],(2S,2'S)-2,2'-Carbonylbis(Azanediyl)Dipentanedioic Acid Others , Ligands for Target Protein for PROTAC
DUPA (N,N''-Carbonylbis[L-glutamic acid]) is used as the targeting moiety to actively deliver DTX for treatment of Prostate-Specific Membrane Antigen (PSMA) expressing prostate cancer.
T25814 MIP-1095 I-131 Iodine I 131 MIP-1095,131I-MIP-1095,Iodine I-131 MIP-1095,(131)I-MIP-1095
MIP-1095 I-131 is a small molecule PSMA inhibitor.
T62423 GCPII-IN-1 TFA
GCPII-IN-1 TFA is a glutamate carboxypeptidase II (GCPII; PSMA) inhibitor scaffold (Ki: 44.3 nM).
T76955 Voxalatamab
Voxalatamab (JNJ-63898081), an IgG4 bispecific antibody targeting PSMA and CD3, demonstrates anti-cancer efficacy in prostate cancer research [1].
T25295 Dcfpyl F-18 18F-DCFPyL
Dcfpyl F-18 is used as a PET imaging agent for prostate-specific membrane antigen (PSMA).
T25293 DCFBC
DCFBC is a low-molecular-weight radiotracer. It targets prostate-specific membrane antigen (PSMA).
T25294 DCFBC F-18 18F-DCFBC
DCFBC F-18 is a radioconjugate containing a low molecular weight tracer, DCFBC, specific for prostate-specific membrane antigen (PSMA) and labeled with the positron-emitting isotope F 18 with potential prostate tumor ima...
T77130 Pasotuxizumab
Pasotuxizumab (BAY 2010112) is a bispecific T-cell engager (BiTE) targeting PSMA and CD3 with dissociation constants (K D) of 47.0 nM and 9.4 nM for PSMA and CD3, respectively. It is utilized in the study of metastatic c...
T38420 GCPII-IN-1
GCPII-IN-1 is a potent inhibitor scaffold targeting glutamate carboxypeptidase II (GCPII), also known as prostate-specific membrane antigen (PSMA). It exhibits a high affinity for GCPII, with a binding affinity (K i ) of...
T78286 Rosopatamab HJ 591
Rosopatamab (HJ 591) is a humanized monoclonal antibody targeting PSMA, utilized in cancer research with a focus on prostate cancer [1] [2].

Compounds

PSMA-11
T28466
Synonym: HBED-CC-PSMA,Psma-hbed-CC,PSMA11
Target:
PSMA–DA1
T40326
Synonym: PSMA–DA1
Target:
Vipivotide tetraxetan
T12573
Synonym: PSMA-617
Target: Others
PSMA-ALB-56
T39831
Synonym:
Target:
PSMA-1007
T69924
Synonym:
Target:
PSMA-IN-3
T78927
Synonym:
Target:
PSMA I&T
T78153
Synonym:
Target: Others
Biotin-NH-PSMA-617
T78412
Synonym:
Target:
Vipivotide tetraxetan Linker
T17233
Synonym: PSMA-617 Linker
Target: Others
PSMA-Val-Cit-PAB-MMAE
T81361
Synonym:
Target:
PSMA617-TCMC TFA
T28467
Synonym: PSMA617-TCMC TFA salt,PSMA617-analog, PSMA617-derivative with TCMC,PSMA-617-TCMC
Target:
Brigimadlin
T69923
Synonym: BI 907828
Target:
Piflufolastat
T31224
Synonym: DCFPYL
Target: Epigenetic Reader Domain
Glu-urea-Lys TFA(1025796-69-3 free base)
T8925L
Synonym:
Target: Others
DUPA(OtBu)-OH
T11122
Synonym:
Target: Others
Glu-urea-Lys
T8925
Synonym:
Target:
CS-0047390
T9280
Synonym: (S)-Di-tert-butyl 2-(3-((S)-6-amino-1-(tert-butoxy)-1-oxohexan-2-yl)ureido)pentanedioate
Target: Others
DUPA
T19301
Synonym: N,N''-Carbonylbis[L-glutamic acid],(2S,2'S)-2,2'-Carbonylbis(Azanediyl)Dipentanedioic Acid
Target: Others, Ligands for Target Protein for PROTAC
MIP-1095 I-131
T25814
Synonym: Iodine I 131 MIP-1095,131I-MIP-1095,Iodine I-131 MIP-1095,(131)I-MIP-1095
Target:
GCPII-IN-1 TFA
T62423
Synonym:
Target:
Voxalatamab
T76955
Synonym:
Target:
Dcfpyl F-18
T25295
Synonym: 18F-DCFPyL
Target:
DCFBC
T25293
Synonym:
Target:
DCFBC F-18
T25294
Synonym: 18F-DCFBC
Target:
Pasotuxizumab
T77130
Synonym:
Target:
GCPII-IN-1
T38420
Synonym:
Target:
Rosopatamab
T78286
Synonym: HJ 591
Target:
Cat No. Product Name Synonyms Targets
T4959 DL-Mannitol Mannitol Others
DL-Mannitol is a osmotic diuretic, it may play a role in reducing off-target 68Ga-PSMA renal uptake

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-00381 PSMA Protein, Human, Recombinant (His) Human HEK293
Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane prote...
TMPY-05269 PSMA Protein, Human, Recombinant (His), Biotinylated Human HEK293
Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane prote...
TMPK-00521 PSMA Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate...
TMPY-06960 PSMA Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane prote...
TMPK-00370 PSMA Protein, Human, Recombinant (hFc) Human HEK293
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate...
TMPK-00371 PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated Mouse HEK293
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate...
TMPK-00522 PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated Cynomolgus HEK293
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate...
TMPY-01390 PSMA Protein, Mouse, Recombinant (His) Mouse HEK293
Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane prote...
TMPY-04078 PSMA3 Protein, Human, Recombinant (His) Human E. coli
PSMA3 Protein, Human, Recombinant (His) is expressed in E. coli with His tag. The predicted molecular weight is 30.7 kDa. Accession number: AAH29402.1
TargetMol