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PSMA617-TCMC TFA

Catalog No. T28467 CAS T28467

Synonyms: PSMA617-TCMC TFA salt, PSMA617-analog, PSMA617-derivative with TCMC, PSMA-617-TCMC

PSMA617-TCMC is a derivative of PSMA-617 with structure modification, in which the caroboxy groups in DOTA ring is replaced by TCMC macrocycle. PSMA-617 is a ligand used to make 177Lu-PSMA-617, which is a radioactive molecule to fight cancer.

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PSMA617-TCMC TFA, CAS T28467

Pack Size	Availability	Price/USD	Quantity
2 mg	Inquiry	$ 789.00
5 mg	Inquiry	$ 1,368.00

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Biological Description

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Description

Synonyms	PSMA617-TCMC TFA salt, PSMA617-analog, PSMA617-derivative with TCMC, PSMA-617-TCMC
Molecular Weight	1659.52
Formula	C65H86F12N14O21S
CAS No.	T28467

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Ahmadzadehfar H, Schlolaut S, Fimmers R, Yordanova A, Hirzebruch S, Schlenkhoff C, Gaertner FC, Awang ZH, Hauser S, Essler M. Predictors of overall survival in metastatic castration-resistant prostate cancer patients receiving [(177)Lu]Lu-PSMA-617 radioligand therapy. Oncotarget. 2017 Oct 7;8(61):103108-103116. doi: 10.18632/oncotarget.21600. eCollection 2017 Nov 28. PubMed PMID: 29262549; PubMed Central PMCID: PMC5732715. 2. von Eyben FE, Roviello G, Kiljunen T, Uprimny C, Virgolini I, Kairemo K, Joensuu T. Third-line treatment and (177)Lu-PSMA radioligand therapy of metastatic castration-resistant prostate cancer: a systematic review. Eur J Nucl Med Mol Imaging. 2017 Dec 16. doi: 10.1007/s00259-017-3895-x. [Epub ahead of print] Review. PubMed PMID: 29247284. 3. Rahbar K, Ahmadzadehfar H, Boegemann M. (177)Lu-PSMA-617 radioligand therapy in mCRPC: ready for phase III trial? Eur J Nucl Med Mol Imaging. 2017 Nov 21. doi: 10.1007/s00259-017-3892-0. [Epub ahead of print] PubMed PMID: 29164300. 4. Eppard E, de la Fuente A, Benešová M, Khawar A, Bundschuh RA, Gärtner FC, Kreppel B, Kopka K, Essler M, Rösch F. Clinical Translation and First In-Human Use of [(44)Sc]Sc-PSMA-617 for PET Imaging of Metastasized Castrate-Resistant Prostate Cancer. Theranostics. 2017 Sep 26;7(18):4359-4369. doi: 10.7150/thno.20586. eCollection 2017. PubMed PMID: 29158832; PubMed Central PMCID: PMC5695136.

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Keywords

PSMA617-TCMC TFA T28467 PSMA-617-TCMC TFA PSMA617-TCMC TFA salt PSMA617-analog, PSMA617-derivative with TCMC PSMA-617-TCMC PSMA617TCMC TFA PSMA617 TCMC TFA inhibitor inhibit

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