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Search Result

Search Results for " prx "

Targets

5-HT Receptor

29

Compounds

9

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T8720 PRX-07034 hydrochloride PRX-07034 5-HT Receptor
PRX-07034 hydrochloride is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and potently decreases food intake and body weight in rodents. PRX-07034 hydrochloride is both a poten...
T16669 PRX-08066 5-HT Receptor
PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that induces selective vasodilation of pulmonary arteries.
T16265 Naluzotan PRX 00023 EGFR , 5-HT Receptor
Naluzotan（PRX 00023） is a novel and potent 5-HT1A agonist with IC50 and Ki values of approximately 20 nM and 5.1 nM, respectively.Naluzotan is a potent hERG K+ channel blocker with an IC50 value of 3800 nM.Naluzotan exhi...
T77751 Imaprelimab PRX-003 Others
Imaprelimab (PRX-003) is a humanized IgG1 κmonoclonal antibody against melanoma cell adhesion molecule (MCAM). Imaprelimab has antitumor activity and can be used to study inflammation, tumors, and psoriasis.
T68113 Naluzotan hydrochloride PRX 00023 hydrochloride EGFR , 5-HT Receptor
Naluzotan hydrochloride (PRX 00023 hydrochloride) is a hERG K+ channel blocker with an IC50 value of 3800 nM and is commonly used in the study of anxiety and depression.Naluzotan hydrochloride is also a novel, potent, an...
T6959 PRX-08066 Maleic acid 5-HT Receptor
PRX-08066 Maleic acid is a selective 5-HT2B receptor antagonist with IC50 of 3.4 nM, prevents the severity of pulmonary arterial hypertension in the MCT rat model. Phase 2.
T21229 Pirenoxine Catalin,PRX
Pirenoxine is an agent with anti-cataractogenesis activity by interacting with calcium ions or selenite which could lead to the formation of lens cataract.
T29115 VRX 03011 Potassium salt PRX-03140,PRX3140,NTC942,NTC-942,PRX-3140,PRX03140
VRX 03011, a 5-HT4 partial agonist, is used potentially for the treatment of Alzheimer's disease.
T80966 Topsalysin PRX-302
Topsalysin, a prostate-specific antigen (PSA)-activated protoxin, comprises a synthetic proaerolysin fusion protein targeting human prostate-specific antigen. This compound has demonstrated tumor-suppressive effects in a...
T12565 PRX933 hydrochloride BVT-933 hydrochloride,GW876167 hydrochloride 5-HT Receptor
PRX933 hydrochloride (GW876167 hydrochloride) is an agonist of 5-HT2C receptor and can be used in studies about hypertension acute treatment.
T80920 Tulinercept OPRX-106,TNFR-Fc,PRX-106
Tulinercept (OPRX-106), a monoclonal antibody, may be utilized in a range of biochemical research applications [1].
T27518 GW-876167 PRX-00933,PNU-183933,GW876167,BVT933,BVT-933
GW-876167, a 5-HT2C agonist, is used potentially for the treatment of obesity and glaucoma.
T12104 MRGPRX1 agonist 1 Others
MRGPRX1 agonist 1 is a highly potent MRGPRX1 (Mas-related G-protein-coupled receptor X1)agonist(EC50 of 50 nM).
T63812 MrgprX2 antagonist-8 Others
MrgprX2 antagonist-8 is an MrgprX2 antagonist that can be used to study inflammatory diseases.
T40271 MrgprX2 antagonist-3 MrgprX2 antagonist-3
MrgprX2 antagonist-3 is a potent inhibitor of MrgprX2. It holds promising potential for investigating skin inflammatory disorders.
T40273 MrgprX2 antagonist-2 MrgprX2 antagonist-2
MrgprX2 antagonist-2 is a potent antagonist of MrgprX2. It holds potential for investigating skin inflammatory disorders.
T80167 αC-Conotoxin PrXA αC-PrXA
αC-Conotoxin PrXA is a neurotoxic paralytic peptide acting as a competitive antagonist of the nicotinic acetylcholine receptor (nAChR), exhibiting inhibitory constants (IC50) of 1.8 nM for the adult α1β1εδ subtype and 3....
T60466 MRGPRX1 agonist 2
MRGPRX1 agonist 2 (compound 1a) is a potent positive allosteric modulator of Mas-related G protein-coupled receptor X1 (MRGPRX1) with an EC 50 value of 0.48 μM. MRGPRX1 agonist 2 has the potential to be used in neuropath...
T63766 MrgprX2 antagonist-7
MrgprX2 antagonist-7 is an anti-allergic agent with significant anti-allergic effects and inhibits mast cell degranulation.
T40270 MrgprX2 antagonist-1 MrgprX2 antagonist-1
MrgprX2 antagonist-1, is a novel MrgprX2 antagonist compound. It exhibits potential for exploration in studying cutaneous inflammatory disorders.
T40176 MrgprX2 antagonist-5 MrgprX2 antagonist-5
MrgprX2 antagonist-5, which acts as a potent antagonist of MrgprX2. It exhibits the ability to effectively inhibit the activity of MrgprX2, making it an ideal candidate for research related to inflammatory skin disorders...
T61332 MRGPRX4 modulator-1
MRGPRX4 modulator-1 (compound 31-2) is a potent antagonist of the mas-related g-protein receptor X4 (MRGPR X4) with an IC50 < 100 nM against MRGPR4. It is utilized for the investigation of MRGPR X4 dependent diseases inc...
T61183 MRGPRX4 modulator-2
MRGPRX4 modulator-2 (compound 1-55) is a highly potent modulator of MRGPR X4, displaying antagonist activity against this receptor with an IC50 value of less than 100 nM. Its application in the research of autoimmune dis...
T60497 MRGPRX1 agonist 3
MRGPRX1 agonist 3 (compound 1f) is a potent positive allosteric modulator of Mas-related G protein-coupled receptor X1 (MRGPRX1) with an EC50 of 0.22 μM. MRGPRX1 agonist 3 can be used for neuropathic pain research[1].
T63549 MRGPRX1 agonist 4
MRGPRX1 agonist 4 is a potent and orally active Mas-related G protein-coupled receptor X1 (MRGPRX1) positive conformation modulator (EC50: 0.1 μM). MRGPRX1 agonist 4 ameliorated the behavioral thermal allergic response i...
T63394 MrgprX2 antagonist-6
MrgprX2 antagonist-6 is a potent antiallergic agent with inhibitory effects on mast cell degranulation.
T40268 MrgprX2 antagonist-4 MrgprX2 antagonist-4
MrgprX2 antagonist-4 and compound B-51 E117, is a potent MrgprX2 antagonist. It specifically targets and inhibits the MrgprX2 receptor, making it suitable for investigating various inflammatory skin disorders.
T76889 Prasinezumab
Prasinezumab (PRX 002), a humanized IgG1 monoclonal antibody targeting aggregated α-synuclein, shows promise for Parkinson's disease research [1].
T28906 T6603185 T-6603185,T 6603185
T6603185 is a novel inhibitor of peroxiredoxin (Prx) and thioredoxin (Trx) systems.

Compounds

PRX-07034 hydrochloride
T8720
Synonym: PRX-07034
Target: 5-HT Receptor
PRX-08066
T16669
Synonym:
Target: 5-HT Receptor
Naluzotan
T16265
Synonym: PRX 00023
Target: EGFR, 5-HT Receptor
Imaprelimab
T77751
Synonym: PRX-003
Target: Others
Naluzotan hydrochloride
T68113
Synonym: PRX 00023 hydrochloride
Target: EGFR, 5-HT Receptor
PRX-08066 Maleic acid
T6959
Synonym:
Target: 5-HT Receptor
Pirenoxine
T21229
Synonym: Catalin,PRX
Target:
VRX 03011 Potassium salt
T29115
Synonym: PRX-03140,PRX3140,NTC942,NTC-942,PRX-3140,PRX03140
Target:
Topsalysin
T80966
Synonym: PRX-302
Target:
PRX933 hydrochloride
T12565
Synonym: BVT-933 hydrochloride,GW876167 hydrochloride
Target: 5-HT Receptor
Tulinercept
T80920
Synonym: OPRX-106,TNFR-Fc,PRX-106
Target:
GW-876167
T27518
Synonym: PRX-00933,PNU-183933,GW876167,BVT933,BVT-933
Target:
MRGPRX1 agonist 1
T12104
Synonym:
Target: Others
MrgprX2 antagonist-8
T63812
Synonym:
Target: Others
MrgprX2 antagonist-3
T40271
Synonym: MrgprX2 antagonist-3
Target:
MrgprX2 antagonist-2
T40273
Synonym: MrgprX2 antagonist-2
Target:
αC-Conotoxin PrXA
T80167
Synonym: αC-PrXA
Target:
MRGPRX1 agonist 2
T60466
Synonym:
Target:
MrgprX2 antagonist-7
T63766
Synonym:
Target:
MrgprX2 antagonist-1
T40270
Synonym: MrgprX2 antagonist-1
Target:
MrgprX2 antagonist-5
T40176
Synonym: MrgprX2 antagonist-5
Target:
MRGPRX4 modulator-1
T61332
Synonym:
Target:
MRGPRX4 modulator-2
T61183
Synonym:
Target:
MRGPRX1 agonist 3
T60497
Synonym:
Target:
MRGPRX1 agonist 4
T63549
Synonym:
Target:
MrgprX2 antagonist-6
T63394
Synonym:
Target:
MrgprX2 antagonist-4
T40268
Synonym: MrgprX2 antagonist-4
Target:
Prasinezumab
T76889
Synonym:
Target:
T6603185
T28906
Synonym: T-6603185,T 6603185
Target:

Recombinant Proteins

Species：
Human (8)
Arabidopsis thaliana (1)
Expression System：
E. coli (6)
Baculovirus Insect Cells (1)
HEK293 Cells (1)
P. pastoris (Yeast) (1)
Tag：
His (4)
N-6xHis (4)
Tag Free (1)
Cat No. Product Name Species Expression System
TMPH-00072 2-Cys Prx A Protein, Arabidopsis thaliana, Recombinant (His) Arabidopsis thaliana P. pastoris (Yeast)
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxide...
TMPY-02201 Peroxiredoxin 6 Protein, Human, Recombinant (His) Human E. coli
PRDX6, a member of antioxidant protein superfamily, plays an important role in oxidative stress, catabolism of lipids and phospholipid lipisomes. Peroxiredoxin 6 (PRDX6) is involved in redox regulation of the cell and is...
TMPY-02208 Peroxiredoxin 5 Protein, Human, Recombinant (His) Human E. coli
Peroxiredoxin 5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 18.5 kDa and the accession number is P30044-2.
TMPJ-00934 PRDX3 Protein, Human, Recombinant Human E. coli
Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and hu...
TMPJ-01098 PRDX4 Protein, Human, Recombinant (His) Human E. coli
Peroxiredoxin-4 (PRDX4) is a member of the AhpC/TSA family. PRDX4 is a cytoplasmic protein and contains one thioredoxin domain. PRDX4 exists in homodimer or heterodimer with PRDX1. PRDX4 reduces hydrogen peroxide and alk...
TMPJ-00933 PRDX5 Protein, Human, Recombinant (His) Human HEK293 Cells
Peroxisomes are essential organelles that participate in multiple important metabolic processes, including the β-oxidation of fatty acids, plasmalogen synthesis, and the metabolism of reactive oxygen species (ROS). Perox...
TMPY-01276 Peroxiredoxin 1 Protein, Human, Recombinant (His) Human E. coli
Peroxiredoxin 1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.9 kDa and the accession number is A0A384NPQ2.
TMPY-02200 Peroxiredoxin 2 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Peroxiredoxin 2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 24 kDa and the accession number is P32119.
TMPH-01640 MRGPRX2 Protein, Human, Recombinant (His) Human E. coli
Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules ...
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