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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T24654 | PPT | ||
PPT is a modulator of water-heme interactions of CYP2C9d and CYP125A1 in low-spin P450 complexes. | |||
T16566 | Propyl pyrazole triol | PPT | Estrogen Receptor/ERR , Estrogen/progestogen Receptor |
Propyl pyrazole triol (PPT) is a selective agonist of estrogen receptor alpha. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: ... | |||
T2810 | (20S)-Protopanaxatriol | 20(S)-APPT,g-PPT | Apoptosis , Estrogen Receptor/ERR , Glucocorticoid Receptor , Estrogen/progestogen Receptor , Liver X Receptor |
(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid receptor. | |||
T63534 | PPTN hydrochloride | P2Y Receptor | |
PPTN hydrochloride is a potent, high-affinity, competitive, highly selective P2Y14 receptor antagonist (KB: 434 pM), but no agonist or antagonist activity at P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12 or P2Y13 receptors, exhib... | |||
T12530 | PPTN | P2Y Receptor | |
PPTN is a high-affinity, competitive and highly selective antagonist of P2Y14 receptor(KB value of 434 pM), with anti-inflammatory and immune activity. | |||
T61167 | PptT-IN-1 | ||
PptT-IN-1 (compound 5j) is a highly potent inhibitor (IC50: 2.8 μM) of phosphopantetheinyl phosphoryl transferase (PptT), a crucial enzyme involved in the biosynthesis of cellular lipids and virulence factors in Mycobact... | |||
T31550 | DMA-CPPTL | DMACPPTL,DMA CPPTL | |
DMA-CPPTL is a prodrug of CPPTL which induces apoptosis in a dose-dependent manner via the ROS/JNK pathway in acute myeloid leukemia. | |||
T61466 | PptT-IN-3 | ||
PptT-IN-3 (compound 5p) is a powerful inhibitor (IC 50 = 3.5 μM) of phosphopantetheinyl phosphoryl transferase (PptT), an indispensable enzyme involved in the synthesis of cellular lipids and virulence factors in Mycobac... | |||
T78714 | PptT-IN-4 | Calcium Channel | |
PptT-IN-4 (Compound 3a) is a PptT inhibitor exhibiting an IC50 of 0.71 μM. It also demonstrates antimycobacterial activity against Mtb H37Rv, with a MIC of 42 μM, and inhibits hERG, hCav1.2, and hNav1.5 channels with IC5... | |||
T61847 | PptT-IN-2 | ||
PptT-IN-2 (compound 5k) is a highly effective inhibitor of phosphopantetheinyl phosphoryl transferase (PptT), with an IC50 of 2.5 μM. PptT is an indispensable enzyme crucial for synthesizing cellular lipids and virulence... | |||
T24655 | PPTN Mesylate | PPTN Mesylate salt | |
PPTN Mesylate is an effective and highly selective antagonist of the P2Y14 receptor. | |||
T37191 | Mu-6S-Palm-β-Glc | ||
Mu-6S-Palm-β-Glc is a fluorogenic substrate of palmitoyl-protein thioesterase (PPT, also known as CLN1), a lysosomal hydrolase that removes long-chain fatty acyl groups from modified cysteine residues in proteins. Mu-6S-... |