Search Result

Search Results for " pd-l2 "

Targets

Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T77075	Spartalizumab	PDR001	PD-1/PD-L1
	Spartalizumab (PDR001) is a humanized immunoglobulin 4 monoclonal antibody that selectively binds to PD-1 at low concentrations and shows high activity. Spartalizumab blocks the interaction with PD-L1 and PD-L2, and can ...		PD-1/PD-L1
T9902	Atezolizumab		Apoptosis , PD-1/PD-L1 , Autophagy
	Atezolizumab anti-PD-L1) is a fully humanized IgG1 monoclonal antibody that blocks the interaction of PD-L1 with both PD-1 and B7.1 but not the interaction of PD-L2 with PD-1.		Apoptosis , PD-1/PD-L1 , Autophagy
T35394	Sintilimab (anti-PD-1)	IBI308,Sintilimab (anti-PD-1)	PD-1/PD-L1
	Sintilimab (IBI308) is a humanized IgG4 monoclonal antibody with significant anti-tumor activity that restores endogenous anti-tumor T-cell responses by binding to PD-1 and thereby blocking the interaction of PD-1 with i...		PD-1/PD-L1
T76850	Dostarlimab
	Dostarlimab (TSR-042) is a humanized monoclonal antibody targeting PD-1 with high affinity, designed to block its interaction with ligands PD-L1 and PD-L2. By competitively inhibiting these interactions, it achieves IC50...
T77023	Geptanolimab
	Geptanolimab (CBT-501), a humanized IgG4κ monoclonal antibody targeting PD-1 (Programmed Death-1), functions by competitively inhibiting the interaction between PD-L1/L2 and PD-1, thereby possessing potential use in canc...
TP1075	AUNP-12 TFA (1353563-85-5 free base)	AUNP-12 TFA,NP-12 TFA
	AUNP-12 TFA (NP-12 TFA) is a polypeptide antagonist in the pd-1 signaling pathway, which has the same antagonistic effect on pd-l1 and pd-l2, and can protect the proliferation and effector function of lymphocytes.
T77003	Ezabenlimab
	Ezabenlimab (BI-754091) is an anti-PD-1 monoclonal antibody (mAb) that exhibits a binding constant (Kd) of 6 nM in CHO cells. It effectively inhibits the interaction between PD-1 and its ligands, PD-L1 and PD-L2, enhanci...
T76020	AUNP-12 TFA
	AUNP-12 TFA (NP-12 TFA), a peptide antagonist of the PD-1 signaling pathway, exhibits equipotent antagonism toward PD-L1 and PD-L2, enhancing lymphocyte proliferation and effector functions. It promotes immune activation...
T76985	Tebotelimab
	Tebotelimab (MGD-013) is a bispecific antibody targeting PD-1 and LAG-3, classified as a human IgG4κ dual-affinity re-targeting (DART) molecule. It exhibits binding affinities with EC50 values of 1.65 nM for PD-1 and 0.4...
T35396	Spartalizumab (anti-PD-1)		PD-1/PD-L1
	Spartalizumab (anti-PD-1) is a useful organic compound for research related to life sciences and the catalog number is T35396.		PD-1/PD-L1
T76945	Cetrelimab
	Cetrelimab (JNJ 63723283; JNJ 3283), a humanized IgG4κ monoclonal antibody (mAb) targeting PD-1, binds to PD-1 (Kd=1.72 nM, HEK293) to prevent its interaction with PD-L1 and PD-L2 (IC50s=111.7 ng/mL and 138.6 ng/mL, resp...

Compounds

Target: Apoptosis, PD-1/PD-L1, Autophagy

Sintilimab (anti-PD-1)

T35394

Synonym: IBI308,Sintilimab (anti-PD-1)

AUNP-12 TFA (1353563-85-5 free base)

TP1075

Synonym: AUNP-12 TFA,NP-12 TFA

Spartalizumab (anti-PD-1)

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04346	PD-L2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPY-05827	PD-L2 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	PD-L2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 48.93 kDa and the accession number is Q9BQ51-1.
TMPY-04957	PD-L2 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	PD-L2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPY-02352	PD-L2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	PD-L2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9WUL5.
TMPY-02436	PD-L2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	PD-L2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.5 kDa and the accession number is Q9WUL5.
TMPY-05282	PD-L2 Protein, Mouse, Recombinant (His), Biotinylated	Mouse	HEK293 Cells
	PD-L2 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9WUL5.
TMPY-00120	PD-L2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	PD-L2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.3 kDa and the accession number is Q9BQ51-1.
TMPK-00166	PD-L2 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine pr...
TMPK-01290	PD-L2 Protein, Cynomolgus, Recombinant (aa 20-220, His)	Cynomolgus	HEK293 Cells
	PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine pr...
TMPY-06281	PD-L2 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293 Cells
	PD-L2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 51.09 kDa and the accession number is Q9BQ51-1.
TMPY-05613	PD-L2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	PD-L2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 25.8 kDa and the accession number is Q9BQ51-1.
TMPY-04225	PD-L2 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	PD-L2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.9 kDa and the accession number is D4AAV6.
TMPY-04223	PD-L2 Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	PD-L2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.2 kDa and the accession number is D4AAV6.
TMPY-06819	PD-L2 Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293 Cells
	PD-L2 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.6 kDa and the accession number is A4GW30.
TMPY-06838	PD-L2 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293 Cells
	PD-L2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is NP_001077068.1.
TMPY-03404	PD-L2 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
	PD-L2 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.6 kDa and the accession number is A4GW30.
TMPY-03738	PD-L2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	PD-L2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is A4GW30.
TMPJ-00181	PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 inhibits the T-cell pr...