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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T25283 | Cytochrome P450 2C9 | Cyp2C9,Human cytochrome P450 2C9,Cytochrome P 450 2C9,S-Mephenytoin 4-hydroxylase | |
Cytochrome P450 2C9 is a cytochrome P-450 subtype that possesses specificity for acidic xenobiotics. It oxidizes a wide range of important clinical drugs under the categories of nonsteroidal anti-inflammatory agents, ant... | |||
T80057 | Cytochrome P450 reductase | ||
Cytochrome P450 reductase, a NADPH-cytochrome reductase, facilitates an optimal conformation of aromatase for substrate binding [1]. | |||
TP2238 | Cytochrome P450 CYP1B1 (190-198) [Homo sapiens] | Others | |
Cytochrome P450 CYP1B1 (190-198) [Homo sapiens] is a small heme protein found loosely associated with the inner membrane of the mitochondrion. | |||
T8038 | 7-Ethoxy-4-Methylcoumarin | Others | |
7-Ethoxy-4-Methylcoumarin is considered an inhibitor of enzymes in cells and has been used in studies of enzyme inhibition and has been used to study the effects of various drugs on the human body. | |||
T21482 | Uniconazole | P450 , ROS Kinase | |
Uniconazole is a plant growth regulator that inhibit cytochrome P450 707As (Ki=68 nM). CYP707As is a major ABA catabolic enzyme that catabolize Abscisic acid, accordingly suppress gibberellin and sterol biosynthesis. | |||
T6S1894 | Linderane | P450 | |
1. Linderane was characterized as a mechanism-based inactivator of CYP2C9. | |||
T3818 | Fraxinol | Others , P450 | |
Fraxinol is a predicted metabolite generated by BioTransformer¹ that is produced by the metabolism of 5, 7-dimethoxy-2h-chromen-2-one. It is generated by cyp1a2, cyp2a6, cyp2b6, cyp2c9, cyp2c19, and cyp2e1 enzymes via an... | |||
T3696 | Polygalaxanthone III | Others , P450 | |
Polygalaxanthone III can significantly inhibit chlorzoxazone 6-hydroxylation catalyzed by CYP2E1. | |||
T17022 | Tebuconazole | P450 , Antifungal | |
Tebuconazole is an agricultural azole fungicide. It can also inhibit CYP51 (IC50s: 0.9 and 1.3 μM for Candida albicans CYP51 and truncated Homo sapiens CYP51, respectively). | |||
T7970 | 7-Ethoxycoumarin | Others | |
7-Ethoxycoumarin, a typical human P450 substrate, is catalyzed by both wild-type and mutant forms of CYP102A1. | |||
T3669 | Curcumenol | (+)-Curcumenol | P450 |
Curcumenol ((+)-Curcumenol), one of the major components of Zedoary turmeric oil, is an antibiotic drug which has anti-Y, anti-inflammation activity. Curcumenol may be safely used without inducing metabolic drug-drug int... | |||
T5594 | Cedrol | P450 , Antifungal | |
Cedrol is a cedrane sesquiterpenoid and a tertiary alcohol,Cedrol inhibits the cytochrome P450 (CYP) isoforms CYP2B6 and CYP3A4 (Kis = 0.9 and 3.4 μM, respectively) | |||
T10953 | Dafadine-A | P450 | |
Dafadine-A is an analog of dafadine and a novel inhibitor of DAF-9 cytochrome P450 in the nematode Caenorhabditis elegans. Mammalian orthologs that also inhibit DAF-9 (CYP27A1). | |||
T21529 | (S)-Mephenytoin | Others | |
(S)-Mephenytoin ((+)-Mephenytoin) anticonvulsant effect. It is a substrate of the cytochrome P450 (CYP) isoform CYP2C19 and can be used to analyze cytochrome P450 metabolism. | |||
TN1650 | Friedelin | P450 , NOS , Caspase , Prostaglandin Receptor | |
Friedelin possesses antioxidant, gastroprotective, anti-diarrhoeal, liver protective, anti-inflammatory, analgesic and antipyretic activities. | |||
T7410 | Furafylline | P450 | |
Furafylline is a selective inhibitor of human cytochrome P450 (CYP)1A2 (IC50 : 0.07 µM), | |||
T11991 | Mefentrifluconazole | P450 , Antifungal | |
Mefentrifluconazole is a potent, selective and orally active fungal CYP51 (Kd= 0.5 nM) inhibitor, but shows less inhibitory activity on human aromatase (IC50=0.92 μM). Mefentrifluconazole is a novel azole derivative and ... | |||
T8079 | α-Terpinyl acetate | Terpinyl Acetate | Others , P450 |
α-Terpinyl acetate is a natural compound found in several essential oils, is a flavouring agent. | |||
TQ0191 | Dihydromethysticin | (+)-Dihydromethysticin | P450 |
Dihydromethysticin ((+)-Dihydromethysticin) is a kavalactone found in Piper methysticum. It has marked activity on the induction of CYP3A23. | |||
T2854 | Phillyrin | Forsythin | P450 , Influenza Virus , AMPK |
Phillyrin (Forsythin) is a novel AMPK activator, has anti-obesity effects in nutritive obesity mice, it can prevent lipid accumulation in HepG2 cells by blocking the expression of SREBP-1c and FAS through LKB1/AMPK activ... |