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Search Results for " p-site "

10

Compounds

Cat No. Product Name Synonyms Targets
T10066 2',5'-Dideoxyadenosine Adenylyl cyclase , Adrenergic Receptor , AChR
2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site (IC50: 3 μM).
T21807 INCA-6 Triptycene-1,4-quinone Others
INCA-6 (Triptycene-1,4-quinone) is a cell-permeable NFAT inhibitor. INCA-6 inhibits of CN-NFAT signaling by targeting of NFAT(P) substrate to the calcineurin (CN) phosphatase site.
T8533 ML318 Others , Antibiotic
ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site). ML318 inhibits P. aeruginosa (PAO1) with IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of...
T16125 MMV390048 Parasite , PI4K
MMV390048 is an antimalarial agent and is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 μM). MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. fal...
TP2352 Septide Substance P (6-11), pyroglutamyl(6)-proline(9)-,6-Glp-9-pro-substance P (6-11)
Septide is an NK1 receptor agonist acting at a site distinct from substance P.
T69382 INDOPY-1
INDOPY-1 is a Nucleotide-Competing Reverse Transcriptase Inhibitor. INDOPY-1 was the first NcRTI discovered, displaying reversible competitive inhibition of dNTP binding. 3,4 Biochemical studies showed that INDOPY-1 arr...
T10453 BACE1-IN-5 Beta Amyloid , BACE
BACE1-IN-5 (Compound 15), a potent β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, demonstrates significant efficacy with an IC50 of 9.1 nM for BACE1 inhibition and an impressive IC50 of 0.82 nM aga...
TN1104 Cyanidin 3-sambubioside chloride Cyanidin-3-O-sambubioside chloride NF-κB , ROS
Cyanidin-3-O-sambubioside chloride is inhibitors of BPDE-induced NF-kB activity. It inhibits the enzyme activity by competing with the substrate for the active site. Cyanidin-3-O-sambubioside chloride has antioxidant act...
T83849 OP-145 TFA acetyl-IGKEFKRIVERIKRFLRELVRPLR-amide,P60.4-Ac
OP-145, a derivative of the antimicrobial peptide LL-37, is a synthetic antimicrobial peptide showing activity against E. coli, P. aeruginosa, C. albicans, and A. niger, with minimum inhibitory concentrations (MICs) of 2...
T37832 CAY10761 CAY10761
CAY10761 is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1; IC50s = 467 and 429 μM for the human and snake venom enzymes, respectively).1,2 It also inhibits mushroom tyrosinase (Ki = 1.9 μM) an...
TargetMol