oxindole — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
Fr16741	Oxindole	Indolin-2-one	Others , HIV Protease
	Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases ...		Others , HIV Protease
T23554	(Z)-FeCP-oxindole		VEGFR , Others
	(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.		VEGFR , Others
T22755	(E)-FeCP-oxindole		VEGFR
	(E)-FeCP-oxindole is an inhibitor of VEGFR2 with IC50 of 214 nM.		VEGFR
T0538	3-Methylindolin-2-one	3-Methyloxindole,3-Methyl-2-oxindole	Others , Endogenous Metabolite
	3-Methylindolin-2-one (3-Methyloxindole) is a reactant for O-acetylation reactions, enantioselective α-amination reactions and for aldol reactions with glyoxal derivatives and more.		Others , Endogenous Metabolite
T5S0658	Corynoxine		Autophagy
	Corynoxine is a natural oxindole alkaloid and induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells.		Autophagy
T26126	Roxindole
	Roxindole is an effective autoreceptor-selective dopamine agonist with additional properties as a serotonin reuptake inhibitor and 5-HT1A agonist. It was originally developed for the therapy of schizophrenic syndromes.
T23250	Roxindole hydrochloride		Others
	Dopamine D2 autoreceptor agonist		Others
TN2938	3-Hydroxy-3-acetonyloxindole		Others
	3-Hydroxy-3-acetonyloxindole is a natural product of Marsdenia, Asclepiadaceae. The catalog number is TN2938 and the CAS number is 33417-17-3. 3-Hydroxy-3-acetonyloxindole can be used as a reference standard.		Others
T37710	5-Hydroxyoxindole		Reactive Oxygen Species
	5-Hydroxyoxindole has been identified as a urinary metabolite of indole, which is produced from tryptophane via the tryptophanase activity of gut bacteria [1]. 5-Hydroxyoxindole has lipid peroxidation inhibition activit...		Reactive Oxygen Species
T9853	STING activator Compound 53		STING
	STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint cons...		STING
T17263	XEN907		Others
	XEN907 is a novel spiro oxindole NaV1.7 blocker. XEN907 also inhibits hNaV1.7 (IC50: 3 nM).		Others
T34259	Rankinidine
	Rankinidine, as an oxindole alkaloid, is isolated from Gelsemium rankinii.
T5143	Corynoxine hydrochloride(6877-32-3(free base))		Autophagy
	Corynoxine hydrochloride is a natural oxindole alkaloid and induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells.		Autophagy
T61379	Anticancer agent 30
	Anticancer agent 30 (compound 6f-Z) is a potent anticancer compound. It belongs to the class of 3-arylidene-2-oxindole derivatives and acts as a selective inhibitor of CDK2. Extensive research has demonstrated its signif...
T75438	Corynoxine hydrochloride
	Corynoxine hydrochloride, a tetracyclic oxindole alkaloid extracted from the hooks of Uncaria macrophylla, functions as a natural autophagy enhancer. It facilitates the removal of alpha-synuclein by activating the Akt/mT...