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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7476 | AS057278 | 3-Methylpyrazole-5-carboxylic acid | Others |
AS057278 (3-Methylpyrazole-5-carboxylic acid) is an D-amino acid oxidase (DAAO) inhibitor. | |||
T3472 | CGS 27023A | MMP | |
CGS 27023A is a non-peptidic, potent, and orally active stromelysin inhibitor. | |||
T1980 | HA14-1 | BCL | |
HA14-1, a Bcl-2/Bcl-XL antagonist, is a non-peptidic ligand of a Bcl-2 surface pocket (IC50: ~9 μM). | |||
T2639 | LY2811376 | Beta Amyloid , Beta-Secretase , BACE | |
LY2811376, an orally available non-peptidic β-secretase(BACE1) inhibitor (IC50: 239-249 nM), can decrease Aβ secretion (EC50: 300 nM). It has 10-fold selectivity towards BACE1 over BACE2, and more than 50-fold inhibition... | |||
T24735 | RP-23618 | ||
RP-23618 is a non-peptidic antagonist of RANTES. | |||
T24625 | PF-184563 | PF184563,PF 184563 | |
PF-184563 is an effective and selective non-peptidic V1a receptor antagonist. | |||
T71596 | Bag-2 | ||
Bag-2 is a Novel potent, non-peptidic bombesin receptor subtype-3 (BRS-3) agonist. | |||
T71595 | Bag-1 | ||
Bag-1 is a novel potent, non-peptidic bombesin receptor subtype-3 (BRS-3) agonist. | |||
T71091 | Y2-Antagonist-2 | ||
Y2-Antagonist-2 is a novel, selective, soluble non-peptidic NPY Y2 receptor antagonist with enhanced CNS exposure. | |||
T71997 | CypD-IN-29 | ||
CypD-IN-29 is a non-peptidic inhibitor of cyclophilin D as a neuroprotective agent in Aβ-induced mitochondrial dysfunction. | |||
T70471 | Cgs 26303 | ||
Cgs 26303 is a potent non-peptidic inhibitor of neutral endopeptidase capable of protecting atrial natriuretic peptide from enzymatic degradation. | |||
T16986 | Tanomastat | BAY 12-9566 | MMP |
Tanomastat is an orally bioavailable and non-peptidic biphenyl matrix metalloproteinases inhibitor. For MMP-2, MMP-3, MMP-9, MMP-13 the Ki values are 11, 143, 301, and 1470 nM respectively. | |||
T10238 | Aclacinomycin A hydrochloride | Aclarubicin hydrochloride | Proteasome |
Aclacinomycin A (Aclarubicin) hydrochloride is a fluorescent molecule and the first described non-peptidic inhibitor showing discrete specificity for the CTRL (chymotrypsin-like) activity of the 20S proteasome. Aclacinom... | |||
T40358 | Ensitrelvir fumarate | S-217622 fumarate | |
Ensitrelvir (S-217622) fumarate is a novel orally active inhibitor, targeting the SARS-CoV-2 3CL protease (IC50 = 13 nM). It demonstrates non-covalent and non-peptidic characteristics. This compound represents a pioneeri... | |||
T74939 | HIV protease-IN-1 | ||
HIV protease-IN-1 (compound 1·succinate), a potent non-peptidic inhibitor of HIV protease, is utilized for AIDS research [1]. | |||
T74097 | THX-B | ||
THX-B, a potent non-peptidic antagonist of the neurotrophin receptor p75 (p75 NTR), is utilized in the study of diabetic kidney disease, neurodegenerative, and inflammatory disorders [1] [2] [3]. | |||
T61964 | RXFP3/4 agonist 2 | RXFP receptor | |
RXFP3/4 agonist 2 is a potent non-peptidic bis-RXFP3/4 agonist that induces the interaction between RXFP3 and β-arrestin-2, and can be used to study diseases caused by metabolic abnormalities. |