Cell Cycle/Checkpoint c-Myc 10074-G5


Catalog No. T3686   CAS 413611-93-5
Purity 97.22% Datasheet

10074-G5 is an inhibitor of c-Myc-Max dimerization.

10074-G5, CAS 413611-93-5
Pack Size Availability Price/USD Quantity
2 mg In stock 45.00
5 mg In stock 64.00
10 mg In stock 89.00
25 mg In stock 162.00
50 mg In stock 270.00
100 mg In stock 490.00
200 mg In stock 686.00
1 mL * 10 mM (in DMSO) In stock 70.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description 10074-G5 is an inhibitor of c-Myc-Max dimerization.
Targets&IC50 c-Myc :ic50 2.8μM(Ki),  
Cell Research
Daudi cells (3 × 108 cells in logarithmic growth) are incubated for 0, 1, 3, 6, or 24 h in 3 ml of complete medium containing 10 μM 10074-G5. After incubation, cells are harvested, split into two samples of 1.5 ml each, and overlaid in microcentrifuge tubes containing 0.5 ml of silicon oil. The tubes are centrifuged at 12,000g for 4 min. After centrifugation, the top 1 ml of medium is removed and stored in cryovials at −70°C until analysis. The remaining medium and silicon oil are carefully removed without disturbing the cell pellets. The sides of the tubes are cleaned with cotton-tipped applicators, and the cell pellets are stored at −70°C until analysis.(Only for Reference)
Cell lines: Daudi cells
Animal Research
Animal Model: Specific-pathogen-free, feC.B-17 SCID mice
Purity 97.22%
Appearance solid
Molecular Weight 332.32
Formula C18H12N4O3
CAS No. 413611-93-5


-20℃ 3 years powder

-80℃ 2 years in solvent

Solubility Information

DMSO: 56 mg/mL (168.5 mM)

Ethanol: 10 mg/mL (30.09 mM)

Water: <1 mg/mL

( < 1 mg/ml refers to the product slightly soluble or insoluble )


References and Literature
1. Yap JL, et al. Bioorg Med Chem Lett. 2013, 23(1):370-4. 2. Clausen DM, et al. J Pharmacol Exp Ther. 2010, 335(3):715-27.

Related Compound Libraries

This product is contained In the following compound libraries:
Bioactive Compound Library Inhibitor Library Anti-cancer Compound Library Apoptosis Compound Library Cell cycle related Compound Library

Related Products

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Nicotinamide-N-oxide 10058-F4 10074-G5 Mycro-3 ML327 Sanggenol L Diphyllin Aaptamine

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