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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T12102 | Mps1-IN-1 | Others | |
Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM ) | |||
T16130 | Mps1-IN-3 | Kinesin | |
Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM). | |||
T1839 | Mps1-IN-2 | Kinesin , PLK | |
Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor. | |||
T70095 | Mps1-IN-1 dihydrochloride | ||
Mps1-IN-1 dihydrochloride, a potent ATP-competitive inhibitor of Mps1 kinase, exhibits an IC50 of 367 nM. It effectively inhibits the activity of Mps1 mitotic kinase and disrupts spindle assembly checkpoint (SAC) functio... | |||
T73229 | Mps1-IN-4 | ||
Mps1-IN-4 is a compound that selectively inhibits Monopolar spindle 1 (Mps1), exhibiting antiproliferative properties useful in cancer research. | |||
T78965 | Mps1-IN-6 | ||
Mps1-IN-6 is a potent Mps1 inhibitor that demonstrates antiproliferative and antitumor activities, exhibiting an IC50 of 2.596 nM [1]. | |||
T73483 | RMS-07 | ||
RMS-07, a covalent inhibitor of Monopolar Spindle Kinase 1 (MPS1/TTK), exhibits a potent inhibitory concentration (IC50) of 13.1 nM. Specifically, it targets a poorly conserved cysteine located in the hinge region of the... | |||
T73308 | Mps1-IN-5 | ||
Mps1-IN-5 is a potent, orally active Mps1 inhibitor exhibiting an IC50 of 29 nM, known for triggering apoptosis and G2/M phase cell cycle arrest. This compound demonstrates antiproliferative and anti-tumor effects by inh... | |||
T37050 | MPS1/TTK Inhibitor | MPS1/TTK Inhibitor | |
MPS1/TTK inhibitor is an inhibitor of monopolar spindle 1 (MPS1/TTK; IC50 = 5.8 nM), a kinase involved in mitotic spindle checkpoint signaling that is overexpressed in certain cancerous tumors. It inhibits MPS1 phosphory... | |||
T71082 | DW532 | ||
DW532 is one of simplified analogues of hematoxylin that has shown broad-spectrum inhibition on tyrosine kinases and in vitro anti-cancer activities. DW532 inhibited EGFR and VEGFR2 in vitro kinase activity (the IC50 val... |