Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 41.00 | |
2 mg | In stock | $ 59.00 | |
5 mg | In stock | $ 97.00 | |
10 mg | In stock | $ 155.00 | |
25 mg | In stock | $ 296.00 | |
50 mg | In stock | $ 547.00 | |
100 mg | In stock | $ 789.00 | |
1 mL * 5 mM (in DMSO) | In stock | $ 115.00 |
Description | Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM). |
Targets&IC50 | Mps1:50 nM |
In vitro | Mps1-IN-3 inhibits the proliferation of U251 glioblastoma cells (IC50: appr 5 μM). Mps1-IN-3 is an effective inhibitor of MPS1 kinase (IC50: 50 nM). Mps1-IN-3 (2 μM) can completely abrogates checkpoint. |
In vivo | Mps1-IN-3 (2 mg/kg, i.v.) sensitizes glioblastoma cells in murine tumor models. It has prolonged survival and no toxicity. |
Molecular Weight | 537.63 |
Formula | C26H31N7O4S |
CAS No. | 1609584-72-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5 mM
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Mps1-IN-3 1609584-72-6 Cytoskeletal Signaling Kinesin Mps1 Mps1 IN 3 Mps1IN3 Monopolar spindle 1 inhibit Mps-1-IN-3 Inhibitor inhibitor