Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 39.00 | |
5 mg | In stock | $ 90.00 | |
10 mg | In stock | $ 169.00 | |
25 mg | In stock | $ 333.00 | |
50 mg | In stock | $ 498.00 | |
100 mg | In stock | $ 723.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 107.00 |
Description | Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM ) |
Targets&IC50 | FAK:440 nM (kd), CLK1:1900 nM (kd), LTK:29 nM (kd), PYK2:280 nM (kd), TNK1:2600 nM (kd), ERK2:2900 nM (kd), ALK:21 nM (kd), InsR:470 nM (kd), IGF1R:750 nM (kd), Mps1:27 nM (kd), GAK:1100 nM (kd), TNK2:3100 nM (kd), INSRR:1200 nM (kd) |
In vitro | Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase(IC50 and a Kd of 367 nM and 27 nM). Mps1-IN-1 also has high affinity for ALK, and LTK, with Kds of 21 and 39 nM, respectively[1]. |
Molecular Weight | 535.66 |
Formula | C28H33N5O4S |
CAS No. | 1125593-20-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 39 mg/mL (72.81 mM)
You can also refer to dose conversion for different animals. More
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