Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 33.00 | |
2 mg | In stock | $ 46.00 | |
5 mg | In stock | $ 75.00 | |
10 mg | In stock | $ 143.00 | |
25 mg | In stock | $ 255.00 | |
50 mg | In stock | $ 413.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 84.00 |
Description | Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor. |
Targets&IC50 | Mps1:145 nM |
Kinase Assay | mTOR activity is assayed using LanthaScreen Kinase kit reagents. PI(3)K α, β, γ and δ activity are assayed using the PI(3)K HTRF assay kit. The concentration of INK128 necessary to achieve inhibition of enzyme activity by 50% (IC50) is calculated using concentrations ranging from 20 μM to 0.1 nM (12-point curve). IC50?values are determined using a nonlinear regression model. |
Molecular Weight | 480.6 |
Formula | C26H36N6O3 |
CAS No. | 1228817-38-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 14.3 mg/mL (30 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Mps1-IN-2 1228817-38-6 Cell Cycle/Checkpoint Cytoskeletal Signaling Kinesin PLK inhibit Inhibitor Monopolar spindle 1 Mps1 Mps1 IN 2 Polo-like Kinase (PLK) Mps1IN2 Mps-1-IN-2 inhibitor