mt-4 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T13783	MT-4		Others
	MT-4 inhibits the adhesion of ovarian cancer (OC) cells to the peritoneum.		Others
T7519	RS-127445 hydrochloride	RS 127445,MT 500	5-HT Receptor
	RS-127445 hydrochloride (MT 500) is a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist(pKi : 9.5).		5-HT Receptor
T11465	Lenacapavir	GS-6207	Others , HIV Protease
	Lenacapavir (GS-6207) is a potent capsid-targeting inhibitor of HIV replication. Lenacapavir shows anti-HIV activity with an EC50 of 100 pM in MT-4 cells.		Others , HIV Protease
T9104	TJ191		Apoptosis
	TJ191 is a selective anti-cancer agent, targeting low TβRIII-expressing malignant T-cell leukemia/lymphoma cells.		Apoptosis
T61395	Mt KARI-IN-4
	Mt KARI-IN-4 (compound 5c) is a highly effective inhibitor of Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI), demonstrating a Ki value of 5.48 μM. Additionally, Mt KARI-IN-4 displays inhibitory propert...
TQ0174	Mavorixafor	AMD-070	CXCR
	Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells (IC...		CXCR
T67833	HIV-1 inhibitor-54		HIV Protease
	HIV-1 inhibitor-54 is a potent HIV-1 inhibitor showing anti-HIV activity (EC50 : 32 nM) against WT HIV-1 (strain IIIB) x in MT-4 cells.HIV-1 inhibitor-54 can be used to study viral infections.		HIV Protease
T10141	4'-Ethynyl-2'-deoxyadenosine		Others
	4'-Ethynyl-2'-deoxyadenosine (4'-E-dA) is a nucleoside reverse transcriptase (RT) inhibitor. It is potent against drug-resistant HIV variants (EC50: 98 nM in MT-4 cells for anti-HIV-1 activity).		Others
T7208	AMD 3465 hexahydrobromide	GENZ-644494 (hexahydrobromide)	HIV Protease , CXCR
	AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity.		HIV Protease , CXCR
T10296	Mavorixafor trihydrochloride	AMD-070 trihydrochloride	HIV Protease
	Mavorixafor trihydrochloride is a selective and orally available CXCR4 antagonist (IC50: 13 nM against CXCR4 125I-SDF binding) and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs (I...		HIV Protease
T29393	3'-Deoxy-4-thiothymidine	Thymidine, 3'-deoxy-4-thio-,Ddthds
	3'-Deoxy-4-thiothymidine can moderately active in protecting HIV-induced cytopathogenicity of MT-2 and CEM cells.
T15045	D77		Others
	D77 is anti-HIV-1 inhibitor. D77 inhibits HIV-1(IIIB) replication by EC50 value of 23.8 μg/ml in MT-4 cell (5.03 μg/ml for C8166 cells).		Others
T62782	HIV-1 inhibitor-34
	HIV-1 inhibitor-34 (compound 5q) is a potent, selective HIV-1 inhibitor that acts on HIV-1 (EC50: 6.4 nM), MT-4 cells (CC50: 16 μM). HIV-1 inhibitor-34 can be used in AIDS research.
T15776	Loviride	R 89439	Others
	Loviride is a non-nucleoside reverse transcriptase inhibitor (IC50: 0.3 µM). Loviride inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells. It is used for reverse transcriptase from HIV-1.		Others
T63813	HIV-1 inhibitor-39
	HIV-1 inhibitor-39 is a potent inhibitor of HIV-1 (EC50>112.88 μM). HIV-1 inhibitor-39 has anti-RT (HIV-1 reverse transcriptase) effect (IC50: 15.75 μM). HIV-1 inhibitor-39 exhibits cytotoxicity against MT-4 cells (CC50:...
T72533	4-Deoxy-4α-phorbol
	4-Deoxy-4α-phorbol, a tetracyclic diterpene identified in E. desmondi, serves as a precursor in the semisynthesis of compounds inhibiting HIV-1-induced cytopathic effects in MT-4 cells and the creation of 4α-phorbol este...
T71009	Dolutegravir SR Isomer
	Dolutegravir SR Isomer is an isomeric derivative of Dolutegravir -- a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripher...
T70881	Dolutegravir RR Isomer
	Dolutegravir RR Isomer is an isomer of Dolutegravir -- a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mono...
T62353	HIV-1 inhibitor-33
	HIV-1 inhibitor-33 (compound 5n) is a potent and selective HIV-1 inhibitor that acts on HIV-1 (EC50: 8.6 nM), MT-4 cells (CC50: 18 μM). HIV-1 inhibitor-33 can be used in the study of AIDS.
T74664	KTX-582
	KTX-582 is a potent IRAK4 degrader, exhibiting DC50 values of 4 nM for IRAK4 and 5 nM for Ikaros. It efficiently induces apoptosis in MYD88 MT DLBCL and has demonstrated effectiveness in inducing in vivo tumor regression...