11
2
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T60083 | MMP-12 Inhibitor | MMP12,MMP408 | MMP |
MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12. | |||
T27603 | INCB3619 | INCB-3619,INCB 3619 | Immunology/Inflammation related |
INCB3619 is a selective and potent inhibitor of ADAM with antitumour effects, inhibiting ADAM10, ADAM17, MMP12 and MMP15. | |||
T10474 | BAY-7598 | Others | |
BAY-7598 is a potent, selective, and orally bioavailable MMP12 inhibitor (IC50s: 0.085, 0.67, and 1.1 nM for human/murine/rat MMP12). | |||
T26720 | AZD-6605 | AZ11920155,AZ-11920155,AZD6605 | |
AZD6605 is a potent, reversible inhibitor of, MMP2, MMP9, MMP12 and MMP13. | |||
T78181 | MMP-7-IN-2 | MMP , Others | |
MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases. | |||
T12414 | PF-00356231 hydrochloride | MMP | |
PF-00356231 hydrochloride is an inhibitor of matrix metalloproteinase MMP-12 with IC50 of 1.4 μM. | |||
T27654 | JG26 | JG 26,JG-26 | MMP , Immunology/Inflammation related |
JG26 is a potent inhibitor of ADAM17, which can inhibit ADAM8, ADAM17, ADAM10 and MMP-12, with IC50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM, respectively, and can be used to study the immune system of the body. | |||
T15015 | CTS-1027 | RS 130830,Ro 1130830 | Others |
CTS-1027 is a small molecule inhibitor of MMPs (IC50s: 0.3 nM, 0.5 nM for MMP2, MMP13). It has > 1,000 fold selectivity over MMP1. | |||
T13249 | UK-370106 | MMP | |
UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-fibronectin by MMP-3 (IC50: 320 nM). | |||
T36492 | CMC2.24 | ||
CMC2.24 (TRB-N0224) is an orally active tricarbonylmethane agent that demonstrates effectiveness in inhibiting Ras activation and the downstream effector ERK1/2 pathway, thus effectively combating pancreatic tumor format... | |||
T31063 | CP-544439 | UNII-516DO4KL5R | |
CP-544439 is an inhibitor of matrix metalloproteinase-13, which has an effect on adipose tissue development. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00942 | MMP-12 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Matrix metalloproteinase-12(MMP12) is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic ac... | |||
TMPY-02869 | MMP-12 Protein, Human, Recombinant (catalytic domain) | Human | E. coli |
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, ... |