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Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PF-00356231 hydrochloride is an inhibitor of matrix metalloproteinase MMP-12 with IC50 of 1.4 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 109.00 | |
5 mg | In stock | $ 328.00 | |
10 mg | In stock | $ 528.00 | |
25 mg | In stock | $ 859.00 | |
50 mg | In stock | $ 1,190.00 | |
100 mg | In stock | $ 1,580.00 | |
500 mg | In stock | $ 3,180.00 |
Description | PF-00356231 hydrochloride is an inhibitor of matrix metalloproteinase MMP-12 with IC50 of 1.4 μM. |
Targets&IC50 | MMP-8:1.7 μM, MMP13:0.65 nM, MMP-3:0.39 μM, MMP-12:1.4 μM, MMP-9:0.98 μM |
In vitro | PF-00356231 hydrochloride shows potency against MMP-13, MMP-3, MMP-9, and MMP-8 with IC50s of 0.65 nM, 0.39 μM, 0.98 μM, and 1.7 μM, respectively. PF-00356231 hydrochloride decreases the IC50 values of MMP-12 (0.014 μM) and MMP-13 (0.27 μM) in the presence AH[1]. |
Molecular Weight | 464.96 |
Formula | C25H21ClN2O3S |
CAS No. | 820223-77-6 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 18.9mg/mL (40.6mM), ultrasonic and warming and heat to 60°C
You can also refer to dose conversion for different animals. More
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PF-00356231 hydrochloride 820223-77-6 Proteases/Proteasome MMP PF-00356231 Hydrochloride PF 00356231 hydrochloride PF00356231 hydrochloride PF00356231 Hydrochloride PF 00356231 Hydrochloride inhibitor inhibit