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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1997L | [Ala17]-MCH acetate | [Ala17]-MCH acetate(359784-84-2 free base) | Melanin-concentrating Hormone Receptor (MCHR) |
[Ala17]-MCH acetate is a selective ligand for MCHR1 with a Ki of 0.16 nM and Kd of 0.37 nM(Eu3+ chelate-labeled). [Ala17]-MCH acetate shows selectivity over MCHR2 with Ki of 34 nM. | |||
TP1996 | MCH(human, mouse, rat) | MCH (human, mouse, rat) | GPR , Melanin-concentrating Hormone Receptor (MCHR) |
MCH(human, mouse, rat) is a potent endogenous agonist at melanin-concentration hormone (MCH) receptors (IC50 values are 0.3 and 1.5 nM and EC50 values are 3.9 and 0.1 nM at MCH1 and MCH2 receptors respectively). Increase... | |||
T13101 | TC-MCH 7c | Melanin-concentrating Hormone Receptor (MCHR) | |
TC-MCH 7c is an oral, selectable and blood-brain barrier penetrating MCH1R antagonist with IC50 performance of 5.6 nM against hMCH1R, and TC-MCH 7c is a phenylpyridone derivative with MCH1R Ki of 3.4 nM against human. In... | |||
T6323 | Oligomycin A | MCH 32 | ATPase , Antibiotic , Antifungal |
Oligomycin A (MCH 32) is an inhibitor of ATP synthase, inhibits oxidative phosphorylation and all the ATP-dependent processes occurring on the coupling membrane of mitochondria. | |||
TP1997 | [Ala17]-MCH | ||
Potent melanin-concentrating hormone (MCH) receptor agonist (EC50 values are 17 and 54 nM at MCH1 and MCH2 receptors respectively). Displays some selectivity towards MCH1 over MCH2 (Ki values are 0.16 and 34 nM respectiv... | |||
TP1102 | MCH (salmon) TFA (87218-84-6 free base) | Melanin Concentrating Hormone, salmon TFA,MCH (salmon) TFA | |
Melanin Concentrating Hormone (MCH), a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus. Melanin Concentrating Hormone is implicated in the control of general arousal and goal-orientated behaviours ... | |||
T11964 | MCH-1 antagonist 1 | P450 | |
MCH-1 antagonist 1 also inhibits CYP3A4 (IC50: 10μM).MCH-1 antagonist 1 is a potent melanin concentrating hormone (MCH-1) antagonist (Ki: 2.6 nM). | |||
TP1104L | Melanin Concentrating Hormone, salmon acetate | MCH (salmon),Melanin Concentrating Hormone, salmon acetate(87218-84-6 free base) | Others , Melanin-concentrating Hormone Receptor (MCHR) |
Melanin Concentrating Hormone, salmon acetate (MCH (salmon)) is a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus. | |||
T75845 | [Ala17]-MCH TFA | ||
[Ala17]-MCH TFA, a selective ligand for MCHR 1 (K i =0.16 nM) over MCHR 2 (K i =34 nM), is an analogue of MCH. When labeled with a [Eu 3+ chelate], [Ala17]-MCH exhibits high affinity for MCHR 1 (K d =0.37 nM) and negligi... | |||
TP1104 | Melanin Concentrating Hormone, salmon | MCH (salmon) | |
Melanin Concentrating Hormone (MCH), a 19 amino acid cyclic peptide, is largely expressed in the hypothalamus. | |||
T75846 | MCH(human, mouse, rat) TFA | ||
MCH (human, mouse, rat) TFA is a potent peptide agonist for MCH receptors, demonstrating strong affinity with binding IC 50 values of 0.3 nM for MCH1R and 1.5 nM for MCH2R. It is notably effective against MCH-2R in a CHO... | |||
T76632 | (Phe13,Tyr19)-MCH (human, mouse, rat) | ||
(Phe13,Tyr19)-MCH (human, mouse, rat) serves as a potent ligand for SLC-1 and S643b receptors and can act as an agonist for these receptors [1]. | |||
T7294 | Aramchol | C20-FABAC | Others |
Aramchol (C20-FABAC), also known as arachidyl amido cholanoic acid, is a conjugate of arachidic acid and cholic acid. It reduces ex vivo cholesterol crystallization in native human bile and dissolves pre-formed cholester... | |||
T11966 | MCHR1 antagonist 2 | HER , Melanin-concentrating Hormone Receptor (MCHR) | |
MCHR1 antagonist 2 is an antagonist of melanin-concentratin hormone receptor 1(MCH1-R, IC50 = 65 nM) and also inhibits hERG. | |||
T38450 | Ac-hMCH(6-16)-NH2 | Ac-hMCH(6-16)-NH2 | |
Ac-hMCH(6-16)-NH2 shows non-selective agonist activity towards both MCH-1R and MCH-2R, which are human MCH receptors in the brain. The compound effectively binds to and activates these receptors, with IC 50 values of 0.1... | |||
T76640 | HMCH-1R antagonist 1 | ||
HMCH-1R Antagonist 1 (Compound 30) serves as an effective and selective antagonist for the human melanin-concentrating hormone receptor 1 (hMCHR1), exhibiting a K_B value of 3.6 nM. It possesses the ability to bind to hM... | |||
T11965 | MCHR1 antagonist 3 | Others | |
MCHR1 antagonist 3, a potent antagonist of the melanin-concentrating hormone receptor-1 (MCHR1), is employed for the regulation of energy metabolism. | |||
T10173 | MCHR1 antagonist 1 | Others | |
MCHR1 antagonist 1 is a selective antagonist of melanin-concentrating hormone-1 (MCH1) receptor (Kb: 1 nM, Ki: 4 nM at human MCH1). | |||
T40896 | Bromchlorbuterol hydrochloride | ||
Bromchlorbuterol hydrochloride is a potent β-adrenergic agonist (β-agonist) compound commonly employed in the investigation of pulmonary conditions such as pulmonary disease and asthma. | |||
T29956 | Amchem R 14 | R14,Polyurethane Y-195,R-14 | |
Amchem R 14 is a biochemical. |