Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MCH-1 antagonist 1 also inhibits CYP3A4 (IC50: 10μM).MCH-1 antagonist 1 is a potent melanin concentrating hormone (MCH-1) antagonist (Ki: 2.6 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | MCH-1 antagonist 1 also inhibits CYP3A4 (IC50: 10μM).MCH-1 antagonist 1 is a potent melanin concentrating hormone (MCH-1) antagonist (Ki: 2.6 nM). |
Targets&IC50 | MCH1:2.6 nM (ki), CYP3A4:10 μM |
In vitro | MCH-1 antagonist 1 also inhibits cytochrome P450 3A4 (CYP3A4) (IC50:10 μM). |
In vivo | The pharmacokinetic profile of MCH-1 antagonist 1 was assessed through its administration to male C57BL/6J DIO mice at a dosage of 30 mg/kg (po). This assessment focused on its impact on body weight, evidenced by an AUC0-6h of 14760 h*ng/mL. |
Molecular Weight | 414.5 |
Formula | C25H26N4O2 |
CAS No. | 1039825-68-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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MCH-1 antagonist 1 1039825-68-7 Metabolism P450 MCH1 antagonist 1 MCH 1 antagonist 1 inhibitor inhibit