20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10057 | LTD4 antagonist 1 | Others | |
LTD4 antagonist 1 is a potent and orally active antagonist of leukotriene D4 (LTD4; Ki: 0.57 nM). | |||
T38128 | Leukotriene D4 | Leukotriene D4 MaxSpec® Standard,LTD4 | |
Leukotriene D4 (LTD4) is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase. It is the first cysteinyl-leukotriene metabolite of LTC4... | |||
T30828 | CGP 35949 | CGP-35949,Cgp-35949,Cgp35949,CGP35949 | Leukotriene Receptor |
CGP 35949 is an LTD4 antagonist with phospholipase inhibitory activity. | |||
T27979 | Masilukast | ICI-D-3523,ZD-3523,ICI D-3523,MCC-847,SA-09012,D-3523 | Leukotriene Receptor |
Masilukast(MCC-847) is an oral leukotriene D4 (LTD4) receptor antagonist for the study of diseases associated with inflammation. | |||
T14326 | AS-35 | Others | |
AS-35 is an orally effective, potent and selective antagonist of leukotrienes, antagonizes LTC4-, LTD4 and LTE4-induced contractions of the ileum. With IC50 values of 8 nM, 4 nM and 3 nM, respectively. It has antiallergi... | |||
T26519 | Ablukast | Ro 23-3544 | Leukotriene Receptor |
Ablukast (Ro 23-3544) is a leuktriene receptor antagonist. Ablukast acts as an anti-asthmatic. | |||
T10501 | YM158 free base | YM-57158 | Others |
YM158 free base is a potent and selective antagonist of TXA2 and LTD4 receptor (pA2s: about 8.81 and 8.87). | |||
T3148 | MK-571 sodium | L-660711 (sodium salt),L-660711 sodium salt,Verlukast sodium,L-660711,MK571,MK-571 sodium salt,Propanoic acid | Leukotriene Receptor , LTR |
MK-571 sodium (L-660711 sodium salt) is a selective, orally active antagonist of the CysLT1 receptor. MK-571 sodium is a multidrug resistance protein-2 (ABCC2, Mrp2) inhibitor used to demonstrate the role of Mrp2 in the ... | |||
T15647 | Tipelukast | MN 001,KCA 757 | Leukotriene Receptor |
Tipelukast (KCA 757) is a novel orally available leukotriene receptor antagonist with anti-inflammatory activity that reduces fibrosis and down-regulates TIMP-1, type 1 collagen.Tipelukast is used in the study of asthma. | |||
T10873 | CP-96486 | Others | |
CP-96486 is a potent and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor (Kis: 20 and 24 nM). | |||
T10054 | CI-949 | Others | |
CI-949 is an allergic mediator release inhibitor, which inhibits leukotriene C4/D4 (LTC4/LTD4), histamine, and thromboxane B2 (TXB2) release (IC50s: 0.5 μM, 11.4 μM and 0.1 μM). | |||
T27912 | LY 290324 | LY-290324,LY290324 | |
LY 290324 is an orally active, potent and selective antagonist of cysteinyl leukotriene (LTD4) receptor. | |||
T10872L | CP 96021 | 5-HT Receptor | |
CP 96021 is a group of 5-HT1 receptors and 5-HT2 receptors antagonists that have anti-inflammatory properties and are non-non-self anti-ulcer compounds for the treatment of gastrointestinal tract and respiratory asthma. | |||
T37493 | 11-trans Leukotriene D4 | 11-trans Leukotriene D4 | |
11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage. 11-trans LTD4 retains about 10-25 % of the potency fo... | |||
T10872 | CP-96021 hydrochloride | Others | |
CP-96021 hydrochloride is a potent and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor receptor (Kis: 34 nM and 37 nM). | |||
T27877 | LY 163443 | LY163443,LY-163443 | |
LY 163443 is an dual receptor antagonist of LTD4 and LTE4. | |||
T71499 | NZ-107 | ||
NZ-107 is an LTB4, LTC4 and LTD4 antagonist. | |||
T37261 | 14,15-Leukotriene D4 | 14,15-Leukotriene D4 | |
14,15-Leukotriene D4 (14,15-LTD4) is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-lipoxygenases (15- and 12-LOs) on arachidonic acid via 15-HpETE and 14,15-LTA4 ... | |||
T0694 | Pranlukast | ONO-1078 | Leukotriene Receptor , IL Receptor , Others , TNF , NF-κB , LTR |
Pranlukast (ONO-1078) is a cysteinyl leukotriene receptor-1 antagonist. It antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered aller... | |||
T16739 | RG-12525 | NID 525 | Leukotriene Receptor , PPAR |
RG-12525(NID 525) is an orally available, selective and competitive leukotriene D (LTD) antagonist that inhibits LTC4, LTD4 and LTE4-induced contraction of guinea pig thin-walled bands, with IC50 values of 2.6 nM, 2.5 nM... |