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Search Results for " ltd4 "

20

Compounds

Cat No. Product Name Synonyms Targets
T10057 LTD4 antagonist 1 Others
LTD4 antagonist 1 is a potent and orally active antagonist of leukotriene D4 (LTD4; Ki: 0.57 nM).
T38128 Leukotriene D4 Leukotriene D4 MaxSpec® Standard,LTD4
Leukotriene D4 (LTD4) is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase. It is the first cysteinyl-leukotriene metabolite of LTC4...
T30828 CGP 35949 CGP-35949,Cgp-35949,Cgp35949,CGP35949 Leukotriene Receptor
CGP 35949 is an LTD4 antagonist with phospholipase inhibitory activity.
T27979 Masilukast ICI-D-3523,ZD-3523,ICI D-3523,MCC-847,SA-09012,D-3523 Leukotriene Receptor
Masilukast(MCC-847) is an oral leukotriene D4 (LTD4) receptor antagonist for the study of diseases associated with inflammation.
T14326 AS-35 Others
AS-35 is an orally effective, potent and selective antagonist of leukotrienes, antagonizes LTC4-, LTD4 and LTE4-induced contractions of the ileum. With IC50 values of 8 nM, 4 nM and 3 nM, respectively. It has antiallergi...
T26519 Ablukast Ro 23-3544 Leukotriene Receptor
Ablukast (Ro 23-3544) is a leuktriene receptor antagonist. Ablukast acts as an anti-asthmatic.
T10501 YM158 free base YM-57158 Others
YM158 free base is a potent and selective antagonist of TXA2 and LTD4 receptor (pA2s: about 8.81 and 8.87).
T3148 MK-571 sodium L-660711 (sodium salt),L-660711 sodium salt,Verlukast sodium,L-660711,MK571,MK-571 sodium salt,Propanoic acid Leukotriene Receptor , LTR
MK-571 sodium (L-660711 sodium salt) is a selective, orally active antagonist of the CysLT1 receptor. MK-571 sodium is a multidrug resistance protein-2 (ABCC2, Mrp2) inhibitor used to demonstrate the role of Mrp2 in the ...
T15647 Tipelukast MN 001,KCA 757 Leukotriene Receptor
Tipelukast (KCA 757) is a novel orally available leukotriene receptor antagonist with anti-inflammatory activity that reduces fibrosis and down-regulates TIMP-1, type 1 collagen.Tipelukast is used in the study of asthma.
T10873 CP-96486 Others
CP-96486 is a potent and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor (Kis: 20 and 24 nM).
T10054 CI-949 Others
CI-949 is an allergic mediator release inhibitor, which inhibits leukotriene C4/D4 (LTC4/LTD4), histamine, and thromboxane B2 (TXB2) release (IC50s: 0.5 μM, 11.4 μM and 0.1 μM).
T27912 LY 290324 LY-290324,LY290324
LY 290324 is an orally active, potent and selective antagonist of cysteinyl leukotriene (LTD4) receptor.
T10872L CP 96021 5-HT Receptor
CP 96021 is a group of 5-HT1 receptors and 5-HT2 receptors antagonists that have anti-inflammatory properties and are non-non-self anti-ulcer compounds for the treatment of gastrointestinal tract and respiratory asthma.
T37493 11-trans Leukotriene D4 11-trans Leukotriene D4
11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage. 11-trans LTD4 retains about 10-25 % of the potency fo...
T10872 CP-96021 hydrochloride Others
CP-96021 hydrochloride is a potent and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor receptor (Kis: 34 nM and 37 nM).
T27877 LY 163443 LY163443,LY-163443
LY 163443 is an dual receptor antagonist of LTD4 and LTE4.
T71499 NZ-107
NZ-107 is an LTB4, LTC4 and LTD4 antagonist.
T37261 14,15-Leukotriene D4 14,15-Leukotriene D4
14,15-Leukotriene D4 (14,15-LTD4) is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-lipoxygenases (15- and 12-LOs) on arachidonic acid via 15-HpETE and 14,15-LTA4 ...
T0694 Pranlukast ONO-1078 Leukotriene Receptor , IL Receptor , Others , TNF , NF-κB , LTR
Pranlukast (ONO-1078) is a cysteinyl leukotriene receptor-1 antagonist. It antagonizes or reduces bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered aller...
T16739 RG-12525 NID 525 Leukotriene Receptor , PPAR
RG-12525(NID 525) is an orally available, selective and competitive leukotriene D (LTD) antagonist that inhibits LTC4, LTD4 and LTE4-induced contraction of guinea pig thin-walled bands, with IC50 values of 2.6 nM, 2.5 nM...
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