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Ablukast

Catalog No. T26519 CAS 96566-25-5

Synonyms: Ro 23-3544

Ablukast (Ro 23-3544) is a leuktriene receptor antagonist. Ablukast acts as an anti-asthmatic.

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Ablukast, CAS 96566-25-5

Pack Size	Availability	Price/USD
1 mg	In stock	$ 72.00
5 mg	In stock	$ 197.00
10 mg	In stock	$ 372.00
25 mg	In stock	$ 629.00
50 mg	In stock	$ 896.00
100 mg	In stock	$ 1,220.00
1 mL * 10 mM (in DMSO)	In stock	$ 226.00

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Purity: 99.18%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Ablukast (Ro 23-3544) is a leuktriene receptor antagonist. Ablukast acts as an anti-asthmatic.

Synonyms	Ro 23-3544
Molecular Weight	498.56
Formula	C28H34O8
CAS No.	96566-25-5

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 60 mg/ml (120.35 mM)

References and Literature

1. Rosenbach T, Csatò M, Czarnetzki BM. Studies on the role of leukotrienes in murine allergic and irritant contact dermatitis. Br J Dermatol. 1988 Jan;118(1):1-6. 2. Sun J, Herman CA. Cardiovascular effects of N-methyl leukotriene C4, a nonmetabolizable leukotriene C4 analogue, and the antagonism of leukotriene-induced hypotension by Ro 23-3544, in the American bullfrog, Rana catesbeiana. Can J Physiol Pharmacol. 1995 Mar;73(3):383-9. 3. Kumar S, et al. Studies of in vitro skin permeation and retention of a leukotriene antagonist from topical vehicles with a hairless guinea pig model. J Pharm Sci. 1992 Jul;81(7):631-4. 4. Meigel W. Allergic contact dermatitis--description of a test model for topical anti-inflammatories with particular reference to the leukotriene-C4 antagonist Ro-23-3544. Arch Dermatol Res. 1991;283(4):278-9.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library GPCR Compound Library Bioactive Compounds Library Max ReFRAME Related Library NO PAINS Compound Library Bioactive Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Ablukast 96566-25-5 GPCR/G Protein Leukotriene Receptor Inhibitor Ro 23-3544 LTC4 bronchoconstriction inhibit inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.