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Search Results for " l861q "

8

Compounds

Cat No. Product Name Synonyms Targets
T5462 Almonertinib HS-10296 EGFR
Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.
T5675 Almonertinib hydrochloride HS-10296 hydrochloride EGFR
Almonertinib hydrochloride (HS-10296 hydrochloride) is a small molecule inhibitor of EGFR-activating mutations and T790M-resistant mutation with limited activity against wild-type EGFR.
T60076 Oritinib SH-1028 EGFR
Oritinib (SH-1028) is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q), EGFR (L858R/T790M), EGFR (d746-750), EGFR (d746-750/T790M), respectively. Oritinib can ...
T73334 Larotinib EGFR , IRAK , Tyrosine Kinases , BTK
Larotinib is an orally active, potent, and broad-spectrum tyrosine kinase inhibitor (TKI) with an IC50 of 0.6 nM for EGFR.
T5168 EGFR-IN-12 EGFR Inhibitor Apoptosis , EGFR
EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.
T2491 AZ-5104 EGFR
AZ5104 is a potent EGFR inhibitor.
T6078 Saracatinib AZD0530 EGFR , Src , BTK , Autophagy
Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.
T39670 Oritinib mesylate SH-1028 mesylate,Oritinib mesylate
Oritinib mesylate (SH-1028) is a highly selective, orally active, pyrimidine-based irreversible inhibitor of epidermal growth factor receptor (EGFR) with a low half maximal inhibitory concentration (IC50) of 18 nM. It de...
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