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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T69868 | ZIKV-IN-K22 | ||
ZIKV-IN-K22 is a potent antiviral agent against a broad range of coronaviruses by targeting membrane-bound viral RNA replication, effectively inhibiting ZIKV with IC50 of 2.1 μM. | |||
T69867 | BN80933 | ||
BN80933 is a dual inhibitor of lipid peroxidation and neuronal nitric oxide synthase; Neuroprotectant. | |||
T4531 | GSK2200150A | Antibacterial | |
GSK2200150A is an anti-tuberculosis (TB) agent identified by high-throughput screening (HTS) campaign. | |||
T6850L | GSK2292767 FA | GSK2292767 FA(1254036-66-2 Free base) | PI3K |
GSK2292767 FA is a potent and selective inhibitor of PI3Kδ (pIC50 : 10.1).GSK2292767 FA is more than 500-fold more selective than other PI3K isoforms.GSK2292767 FA can be used in the study of respiratory diseases. | |||
T11481 | GSK2239633A | CCR | |
GSK2239633A is an allosteric antagonist of CC-chemokine receptor 4 (CCR4) with a pIC50 of 7.96 for the binding of [125I]-TARC to human CCR4. | |||
T2281 | GSK2256098 | GSK 2256098,GSK-2256098,GTPL7939 | Apoptosis , FAK |
GSK2256098 (GTPL7939) is a small molecule FAK kinase inhibitor. | |||
T15430 | GSK2256294A | GSK 2256294 | Others , Epoxide Hydrolase |
GSK2256294A (GSK 2256294) is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively. | |||
T25469 | GSK223 | GSK 223,GSK-223 | |
GSK223 is an iE-DAP-stimulated IL-8 release inhibitor via the NOD1 signaling pathway. | |||
T6850 | GSK2292767 | PI3K | |
GSK2292767 is a potent and selective PI3Kδ inhibitor. | |||
T11482 | GSK2245035 | Others | |
GSK2245035 is a highly selective intranasal TLR7 agonist with preferential Type-1 interferon (IFN)-stimulating properties (pEC50s: 9.3 and 6.5 for IFNα and TFNα). It effectively suppresses allergen-induced Th2 cytokine p... | |||
T69830 | GSK2239633 | ||
GSK2239633 is a potent CC-chemokine receptor 4 antagonist with pIC50 of 7.9. The CC-chemokine receptor 4 (CCR4) is thought potentially to play a critical role in asthma pathogenesis due to its ability to recruit type 2... | |||
T74660 | M4K2234 | ||
M4K2234 (compound 26b), an ALK2 inhibitor, demonstrates selective inhibition of ALK2 and ALK5 with IC50 values of 5 nM and 2144 nM, respectively. Serving as a chemical probe for ALK1 and ALK2 protein kinases, M4K2234 hol... | |||
T27459 | GSK2263167 | GSK-2263167,GSK 2263167 | |
GSK2263167 is an agonist of S1P1 receptor. | |||
T27457 | GSK2210875 | GSK-2210875,GSK 2210875 | |
GSK2210875 is a mGluR5 antagonist with oral activity. |