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Search Results for " jh1 "

7

Compounds

Cat No. Product Name Synonyms Targets
T13237L Ropsacitinib Tyk2-IN-8,PF-06826647 Tyrosine Kinases
Ropsacitinib (PF-06826647) is a selective TYK2 inhibitor, which binds to TYK2 catalytically active JH1 domain (IC50: 17 nM).
T39858 NVP-BSK805 trihydrochloride NVP-BSK805 trihydrochloride
NVP-BSK805 trihydrochloride is a potent ATP-competitive inhibitor of JAK2, exhibiting IC50 values of 0.48 nM, 31.63 nM, 18.68 nM, and 10.76 nM against JAK2 JH1, JAK1 JH1, JAK3 JH1, and TYK2 JH1, respectively.
T5049 NVP-BSK805 NVP-BSK805 2HCl,BSK 805 Tyrosine Kinases , JAK
NVP-BSK805 (BSK 805) is an ATP-competitive JAK2 inhibitor.
T14687 Deucravacitinib BMS-986165 Tyrosine Kinases , JAK , IFNAR , Interleukin
Deucravacitinib (BMS-986165) inhibits IL-12/23 and type I IFN pathways[1][2]. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases. Which selectively bi...
T13235 Tyk2-IN-7 Others
Tyk2-IN-7 is an inhibitor of TYK2 JH2, binds to the TYK2 JH2 domain (IC50: 0.00053 μM; Ki.app: 0.00007 μM).
T13232 TyK2-IN-2 PDE
TyK2-IN-2 is a selective inhibitor of TYK2 (IC50s: 7 nM, 0.1 μM, and 0.05 μM for TYK2 JH2, IL-23, and IFNα).
T13234 Tyk2-IN-5 Others
Tyk2-IN-5 is a selective and orally active inhibitor of Tyk2 JH2 (Ki: 0.086 nM for Tyk2 JH2; IC50: 25 nM for IFNα).
TargetMol