Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ropsacitinib (PF-06826647) is a selective TYK2 inhibitor, which binds to TYK2 catalytically active JH1 domain (IC50: 17 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 243.00 | |
2 mg | In stock | $ 365.00 | |
5 mg | In stock | $ 518.00 | |
10 mg | In stock | $ 749.00 | |
25 mg | In stock | $ 1,160.00 | |
50 mg | In stock | $ 1,570.00 |
Description | Ropsacitinib (PF-06826647) is a selective TYK2 inhibitor, which binds to TYK2 catalytically active JH1 domain (IC50: 17 nM). |
Targets&IC50 | TYK2 JH1:17 nM |
In vitro | Ropsacitinib suppresses JAK1 (IC50=74 nM) and JAK2 (IC50=383 nM) [1]. |
Synonyms | Tyk2-IN-8, PF-06826647 |
Molecular Weight | 383.41 |
Formula | C20H17N9 |
CAS No. | 2127109-84-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (26.08 mM)
You can also refer to dose conversion for different animals. More
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Ropsacitinib 2127109-84-4 Tyrosine Kinase/Adaptors Tyrosine Kinases PF 06826647 Tyk2-IN-8 PF-06826647 PF06826647 inhibitor inhibit