Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tyk2-IN-7 is an inhibitor of TYK2 JH2, binds to the TYK2 JH2 domain (IC50: 0.00053 μM; Ki.app: 0.00007 μM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | Tyk2-IN-7 is an inhibitor of TYK2 JH2, binds to the TYK2 JH2 domain (IC50: 0.00053 μM; Ki.app: 0.00007 μM). |
Targets&IC50 | TYK2 JH1:0.07 nM (Ki.app), TYK2 JH1:0.53 nM |
In vivo | Tyk2-IN-7 inhibits TYK2/JAK1/JAK2 kinase domain. Tyk2-IN-7 (Compound 48) provides robust inhibition in a mouse IL-12-induced IFNγ pharmacodynamic model as well as efficacy in an IL-23 and IL-12-dependent mouse colitis model. |
Molecular Weight | 401.46 |
Formula | C18H15D3N6O3S |
CAS No. | 1609391-90-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Tyk2-IN-7 1609391-90-3 Others Tyk2IN7 Tyk2 IN 7 Tyk-2-IN-7 inhibitor inhibit