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Search Result

Search Results for " itf "

Targets

Guanylate cyclase

16

Compounds

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T34648 Sinitrodil ITF296,ITF-296,ITF 296 Guanylate cyclase
Sinitrodil (ITF-296) is a guanylate cyclase stimulant that may be used in the treatment of myocardial ischemia and angina pectoris.
T6279L Givinostat hydrochloride ITF2357 hydrochloride,Givinostat HCl,ITF2357,ITF 2357,ITF-2357,ITF2357 HCl HDAC
Givinostat hydrochloride (ITF2357 hydrochloride) is an inhibitor of HDAC with IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat hydrochloride exhibits anti-inflammatory, anti-angiogenic, and antineopla...
T6279 Givinostat hydrochloride monohydrate ITF2357,ITF-2357 hydrochloride monohydrate,Givinostat,Gavinostat hydrochloride monohydrate HDAC
Givinostat hydrochloride monohydrate (ITF2357) is an HDAC inhibitor.
T69735 ITF3756 HDAC
ITF3756 is a selective HDAC6 inhibitor.
T27581 Icrocaptide ITF 1697,ITF-1697,ITF1697
Icrocaptide is used potentially for the treatment of acute myocardial infarction.
T27597 Imidazole Salicylate ITF-182,ITF182,ITF 182,Salizolo,Selezen
Imidazole Salicylate, a non-steroidal anti-inflammatory drug, has limited inhibitory effects on prostaglandin synthesis.
T71894 AZD3229 Tosylate
AZD3229 Tosylate is a highly potent inhibitor targeting mutant forms of the pan-KIT enzyme, with a primary application in the treatment of gastrointestinal stromal tumors (GISTs).
T36629 Givinostat
Givinostat (ITF-2357) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat (ITF2357) suppresses total LPS-induced IL-1β production robustly compared with the reduction by ITF30...
T7847 Apelin-13 triTFA(217082-58-1(free base)) Others
Apelin-13 triTFA is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50 value of 0.37 nM.
T7740 Protease-Activated Receptor-4 diTFA Protease-Activated Receptor-4 diTFA(245443-52-1(free base)) Protease-activated Receptor
Protease-Activated Receptor-4 diTFA,2454 is the proteinase-activated receptor-4 (PAR4)agonist
T77923 BSJ-03-204 triTFA CDK
BSJ-03-204 triTFA is a potent and selective Cereblon- and CDK-targeted PROTAC (PROteolysis TArgeting Chimera) featuring Palbociclib-based ligands for the degradation of CDK4/6. It exhibits IC50 values of 26.9 nM for CDK4...
T11330 FTI-2148 diTFA Others
FTI-2148 diTFA, a dual inhibitor targeting both farnesyl transferase (FT-1) and geranylgeranyl transferase-1 (GGT-1), functions as a RAS C-terminal mimetic. It exhibits potent inhibitory capabilities with IC50 values of ...
T81949 Lanreotide diTFA BIM 23014 diTFA
Lanreotide (BIM 23014) diTFA, a somatostatin analogue, exhibits antineoplastic activity and may be utilized in carcinoid syndrome research [1] [2].
T81380 PROTAC EGFR degrader 7 diTFA PROTACs
PROTAC EGFR degrader 7 (compound 13b) is a potent, selective, CRBN-recruiting EGFRL858R/T790M degrader with a DC50 of 13.2 nM. It effectively inhibits proliferation of NCI-H1975 cells with an IC50 of 46.82 nM, induces ap...
TP1127 Nemifitide diTFA INN 00835 diTFA 5-HT Receptor
Nemifitide diTFA (INN 00835 diTFA) is a synthetic pentapeptide, a peptide like melanocyte suppressor factor (MIF) that can cross the blood-brain barrier and has potent antidepressant activity.
T124352 Dihydrocitflavanone
Dihydrocitflavanone is a useful organic compound for research related to life sciences and the catalog number is T124352.

Recombinant Proteins

Species：
Human (1)
Mouse (1)
Expression System：
HEK293 Cells (2)
Tag：
C-6xHis (1)
C-His (1)
Cat No. Product Name Species Expression System
TMPY-04828 TFF3 Protein, Human, Recombinant (His) Human HEK293 Cells
Trefoil factor family (TFF) peptides are involved in the maintenance of epithelial integrity and epithelial restitution. Trefoil factor-3 (TFF3) is an estrogen-regulated gene associated with prognosis in different types ...
TMPJ-01173 TFF3 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Trefoil factors (TFF) are secretory products of mucin producing cells. They play a key role in the maintenance of the surface integrity of oral mucosa and enhance healing of the gastrointestinal mucosa by a process calle...
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