ido-1-in-1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7181	IDO-IN-1		Indoleamine 2,3-Dioxygenase (IDO)
	IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor( IC50 values of 59 and 12 nM for human IDO enzymatic activity and HeLa cell assays, respectively.)		Indoleamine 2,3-Dioxygenase (IDO)
T4142	PCC0208009	IDO inhibitor 1,DO-IN-2,IDO-IN-2	Indoleamine 2,3-Dioxygenase (IDO)
	PCC0208009 (IDO-IN-2) is an IDO inhibitor.		Indoleamine 2,3-Dioxygenase (IDO)
T11623	IDO/TDO-IN-1		Others
	IDO/TDO-IN-1 is an orally active dual indoleamine-2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50s: 9.7 and 47 nM).		Others
T11901	IDO1-IN-5		IDO , Indoleamine 2,3-Dioxygenase (IDO)
	IDO1-IN-5 is a selective, potent and brain penetrated inhibitor of IDO1 activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.		IDO , Indoleamine 2,3-Dioxygenase (IDO)
T20513	IDO1-IN-1	IDO1 inhibitor 1,2 HzBTZ,IDO1IN1,2-HzBTZ,IDO1-inhibitor-1	IDO
	IDO1-IN-1 (2 HzBTZ) is an indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor.		IDO
T11624	IDO1-IN-2		IDO
	IDO1-IN-2 is a potent and selective IDO1 inhibitor with IC50s of 81 nM, 59 nM (mouse), and 28 nM (rat), respectively. It has anti-cancer activity.		IDO
T12801	(S)-IDO1-IN-5		Others
	(S)-IDO1-IN-5 is an active S-isomer of IDO1-IN-5. (S)-IDO1-IN-5 binds to IDOL(IC50 value less than 1.5 µΜ).		Others
T12668	(Rac)-IDO1-IN-5		Others
	(Rac)-IDO1-IN-5 is a racemate of IDO1-IN-5, a potent, selective, and brain-penetrating inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity. It specifically binds to apo-IDO1, which lacks heme, instead of mature he...		Others
T39888	IDO1-IN-7	IDO1-IN-7
	IDO1-IN-7, a potent and selective indoleamine-2,3-dioxygenase-1 (IDO1) inhibitor, exhibits high potency with an IC 50 of 6.1 nM in the cellular assay (SKOV3). Apart from its inhibitory properties, IDO1-IN-7 also demonstr...
T39946	IDO1-IN-12	IDO1-IN-12
	IDO1-IN-12 is a potent and orally available IDO1 inhibitor.
T39839	IDO1-IN-11	IDO1-IN-11
	IDO1-IN-11 is an IDO1 inhibitor with an IC 50 value of 0.6 nM.
T11616	IDO-IN-13	GS-4361	IDO , Indoleamine 2,3-Dioxygenase (IDO)
	IDO-IN-13 (GS-4361) is a potent indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor (EC50: 17 nM).		IDO , Indoleamine 2,3-Dioxygenase (IDO)
T4S0051	Coptisine sulfate		Indoleamine 2,3-Dioxygenase (IDO)
	1. Coptisine sulfate has growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program.		Indoleamine 2,3-Dioxygenase (IDO)
T5S0802	Palmatine	Berbericinine,Burasaine	Indoleamine 2,3-Dioxygenase (IDO) , AChR , AChE , Aurora Kinase
	1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery,...
T5S0053	Coptisine	Coptisin	Indoleamine 2,3-Dioxygenase (IDO)
	1. Coptisine (Coptisin) treatment increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2, 3-dioxygenase . 2. Coptisine treats myocardial I/R likely through suppressing myocardial ...		Indoleamine 2,3-Dioxygenase (IDO)
T11618	IDO-IN-4		Others
	IDO-IN-4 is an indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor.		Others
T11619	IDO-IN-5	NLG-1489	IDO
	IDO-IN-5 is an indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 1-10 μM).		IDO
T11621	IDO-IN-8	NLG-1487	IDO
	IDO-IN-8 is an indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50: 1-10 μM).		IDO
T39089	Acid secretion-IN-1
	Acid secretion-IN-1, a polycyclic compound, is synthesized for its application as an IDO inhibitor in synthetic experiments.
T40211	EIF4E-IN-1	eIF4E-IN-1
	eIF4E-IN-1 (WO2021003194A1, compound Y), is a highly effective inhibitor of eIF4E, a key protein involved in immunosuppression. By targeting immune checkpoint proteins such as PD-1, PD-L1, LAG3, TIM3, and IDO, eIF4E-IN-1...