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Search Results for " hif-1alpha "

Targets

6

Compounds

2

Natural Products

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T36711 FM19G11 FM19G11,HIF-1alpha/2alpha Inhibitor HIF
FM19G11 is an inhibitor of hypoxia inducible factor (HIF) α-subunit (IC50 = 80 nM in hypoxia induced luciferase assay).
T3494 LW6 HIF-1α inhibitor,CAY10585,LW8 Apoptosis , Dehydrogenase , HIF/HIF Prolyl-Hydroxylase , HIF
LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.
T4381 Lificiguat YC-1 Others , Guanylate cyclase , HIF
Lificiguat (YC-1) is an nitric oxide (NO)-independent activator of soluble guanylyl cyclase(sGC) and an inhibitor of Hypoxia-inducible factor-1alpha (HIF-1alpha).
T27028 CJ-3-60 CJ 3-60,CJ3-60,CJ-360,CJ360,CJ 360
CJ-3-60, an anti-HIF-1alpha agent, inhibits HIF-1alpha and cellular VEGF proteins.
T28395 PG-928310
PG-928310 has anti-HIF-1alpha activity.
T70903 KRH102053
KRH102053 is a HIF-1alpha inhibitor. KRH102053 decreased the protein level of HIF-1alpha and the mRNA levels of HIF-regulated downstream target genes, such as vascular endothelial growth factor, aldolase A, enolase 1 an...
Cat No. Product Name Synonyms Targets
T21494 Oligomycin HIF
Oligomycin is an antifungal antibiotic that is an inhibitor of H+-ATP synthetase. The Oligomycin blocks oxidative phosphorylation and the electron transport chain. Oligomycin inhibited HIF-1alpha expression in hypoxic tu...
T6429 Caffeic Acid Phenethyl Ester Phenylethyl Caffeate,CAPE Apoptosis , NF-κB
Caffeic Acid Phenethyl Ester (Phenylethyl Caffeate) (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01709 HIF-1 alpha Protein, Human, Recombinant (His) Human E. coli
HIF-1 alpha, also known as HIF1A, contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain, and 2 PAS (PER-ARNT-SIM) domains. It is one of the two subunits of Hypoxia-inducible factor-1 (...
TMPY-04671 MCP-5 Protein, Mouse, Recombinant (His) Mouse P. pastoris (Yeast)
Ccl12 prevented initiation of the reparative response by prolonging inflammation and inhibiting fibroblast conversion to myofibroblasts, resulting in diminished scar formation. Macrophage secretion of Ccl12 directly impa...
TargetMol