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Search Results for " hdm "

9

Compounds

Cat No. Product Name Synonyms Targets
T5555 Siremadlin NVP-HDM 201 E1/E2/E3 Enzyme
Siremadlin (NVP-HDM 201) is a potent, orally bioavailable and highly specific p53-MDM2 interaction inhibitor.
T70328 HDM-201 succinate
HDM-201 succinate is an orally bioavailable human double minute 2 homolog (HDM2) inhibitor with potential antineoplastic activity.
T70327 OD38
OD38 is a novel potent and selective receptor-interacting protein kinase 2 (ripk2) inhibitor
T15259 Evatanepag CP-533536 free acid Prostaglandin Receptor
Evatanepag (CP-533536 free acid) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.CP-533536 demonstrated the ability to heal fractures when administered l...
T75175 JHDM-IN-1
JHDM-IN-1 (Compound 1), a Jumonji C domain-containing HDMs (JHDM) inhibitor, exhibits IC50s of 3.4 μM against JMJD2C, 4.3 μM against JMJD2A, 5.9 μM against JMJD2E, 10 μM against PHF8, and 43 μM against JMJD3, showcasing ...
T72877 P53-HDM2-IN-1
p53-HDM2-IN-1 is a potent inhibitor of the p53-HDM2 protein-protein interaction, demonstrating an inhibitory concentration (IC 50) of 0.103 μM. This compound has significant applications in cancer research.
T38039 (E)-C-HDMAPP (ammonium salt)
Synthetic and natural alkyl phosphates, also known as phosphoantigens, stimulate the proliferation of γδ-T lymphocytes. Isopentenyl pyrophosphate, and related derivatives including (E)-hydroxy-dimethyl-allyl pyrophosphat...
T1798 RITA NSC 652287,RITA (NSC 652287) Mdm2 , DNA Alkylator/Crosslinker , p53 , Autophagy
RITA (NSC-652287)(NSC-652287) induced cross-links of both DNA-DNA and DNA-protein with no detectable DNA single-strand breaks. RITA, like nutlin-3, can disrupt the p53/Mdm2 interaction.
T81436 PNC-27
PNC-27, an anticancer peptide with an HDM-2-binding domain, exhibits antitumor activity and has potential applications in acute myeloid leukemia research [1] [2] [3].
TargetMol