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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5555 | Siremadlin | NVP-HDM 201 | E1/E2/E3 Enzyme |
Siremadlin (NVP-HDM 201) is a potent, orally bioavailable and highly specific p53-MDM2 interaction inhibitor. | |||
T70328 | HDM-201 succinate | ||
HDM-201 succinate is an orally bioavailable human double minute 2 homolog (HDM2) inhibitor with potential antineoplastic activity. | |||
T70327 | OD38 | ||
OD38 is a novel potent and selective receptor-interacting protein kinase 2 (ripk2) inhibitor | |||
T15259 | Evatanepag | CP-533536 free acid | Prostaglandin Receptor |
Evatanepag (CP-533536 free acid) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.CP-533536 demonstrated the ability to heal fractures when administered l... | |||
T75175 | JHDM-IN-1 | ||
JHDM-IN-1 (Compound 1), a Jumonji C domain-containing HDMs (JHDM) inhibitor, exhibits IC50s of 3.4 μM against JMJD2C, 4.3 μM against JMJD2A, 5.9 μM against JMJD2E, 10 μM against PHF8, and 43 μM against JMJD3, showcasing ... | |||
T72877 | P53-HDM2-IN-1 | ||
p53-HDM2-IN-1 is a potent inhibitor of the p53-HDM2 protein-protein interaction, demonstrating an inhibitory concentration (IC 50) of 0.103 μM. This compound has significant applications in cancer research. | |||
T38039 | (E)-C-HDMAPP (ammonium salt) | ||
Synthetic and natural alkyl phosphates, also known as phosphoantigens, stimulate the proliferation of γδ-T lymphocytes. Isopentenyl pyrophosphate, and related derivatives including (E)-hydroxy-dimethyl-allyl pyrophosphat... | |||
T1798 | RITA | NSC 652287,RITA (NSC 652287) | Mdm2 , DNA Alkylator/Crosslinker , p53 , Autophagy |
RITA (NSC-652287)(NSC-652287) induced cross-links of both DNA-DNA and DNA-protein with no detectable DNA single-strand breaks. RITA, like nutlin-3, can disrupt the p53/Mdm2 interaction. | |||
T81436 | PNC-27 | ||
PNC-27, an anticancer peptide with an HDM-2-binding domain, exhibits antitumor activity and has potential applications in acute myeloid leukemia research [1] [2] [3]. |