galectin — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T79380	Galectin-3/galectin-8-IN-1		Galectin
	Galectin-3/galectin-8-IN-1 (Compound 53) serves as a dual inhibitor of the Galectin-3 and galectin-8 C-terminal domains, exhibiting dissociation constants (Kd) of 4.12 μM for Galectin-3 and 6.04 μM for galectin-8. It eff...		Galectin
T79381	Galectin-3/galectin-8-IN-2		Galectin
	Galectin-3/galectin-8-IN-2 (Compound 57) is a dual inhibitor targeting the C-terminal domains of Galectin-3 and galectin-8, exhibiting dissociation constants (Kd) of 12.8 μM and 2.06 μM, respectively. It effectively inhi...		Galectin
T64040	Galectin-3-IN-2
	Galectin-3-IN-2 is a potent inhibitor of polyvalent galactose lectin-3, with an IC50 value of 8.3 μM for Gal-3. Galectin-3 is involved in many metabolic processes associated with cancer.
T74538	Galectin-3 antagonist 2		Galectin
	Galectin-3, a β-galactoside-specific carbohydrate recognition protein (lectin), facilitates the migration of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) cells and demonstrates resistance to pharmaceutical int...		Galectin
T61014	Galectin-8-IN-1
	Galectin-8-IN-1 is a selective ligand for the galectin-8 N-terminal domain (galectin-8N) with a Kd value of 48 μM. Galectin-8-IN-1 is 15-fold more selective than galectin-3 and even better than other mammalian galectins.
T62454	Galectin-3-IN-1
	Galectin-3-IN-1 (Compound 1) is a potent inhibitor of polyvalent galactose lectin-3 (Gal-3). Galectin-3 is involved in many metabolic processes associated with cancer.
T82605	DB21, Galectin-1 Antagonist		Galectin
	DB21, Galectin-1 Antagonist, is a peptidomimetic conjugated with dibenzofuran, serving as an allosteric inhibitor of galectin-1 (GAL1) interactions with glycans on cell surfaces. This compound enhances the inhibition of ...		Galectin
TQ0265	Indolelactic acid		Endogenous Metabolite
	Indolelactic acid is a metabolite of tryptophan in Azotobacter vinelandii cultures.		Endogenous Metabolite
T16413	OTX008	Calixarene 0118,PTX008	Galectin
	OTX008 (PTX008) is a selective galectin-1 inhibitor.		Galectin
T15372	GB1107	(2R,3R,4S,5R,6R)-2-(3,4-dichlorophenyl)sulfanyl-6-(hydroxymethyl)-4-[4-(3,4,5-trifluorophenyl)triazol-1-yl]oxane-3,5-diol	Galectin
	GB1107 is an effective and selective Galectin-3 inhibitor with a Kd of 37 nM.		Galectin
T5121	TD139		Galectin
	TD139 is an inhaled galectin-3 inhibitor (Kd: 14 nM).		Galectin
T11346L	G3-C12 acetate(848301-94-0 free base)		Galectin
	G3-C12 acetate shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.		Galectin
T38074	Thiodigalactoside		Galectin
	Thiodigalactoside (TDG), a non-metabolizable disaccharide, serves as an orally active, potent galectin (GAL) inhibitor, exhibiting Kd values of 24 μM and 49 μM for GAL1 and GAL3, respectively. Demonstrating anti-inflamma...		Galectin
T11346	G3-C12		Others
	G3-C12 shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.		Others
T75986	G3-C12 TFA
	G3-C12 (TFA), a galectin-3 binding peptide, demonstrates anticancer activity with a dissociation constant (K d) of 88 nM.
T69874	LLS30
	LLS30 is an allosteric inhibitor of Galectin-1 (Gal-1). LLS30 decreases Gal-1 binding affinity to its binding partners, and potentially overcomes metastatic castration-resistant prostate cancer (mCRPC).
TP1294	G3-C12 TFA (848301-94-0 free base)	G3-C12 TFA
	G3-C12 TFA Salt is a specific galectin-3 binding peptide with Ksubdsub of 88 nM and shows anticancer activity.
T63485	Apoptosis inducer 8
	Apoptosis inducer 8 is a galectin-1 (gal-1)-mediated apoptosis inducer and a PET imaging agent that significantly reduces gal-1 protein levels and can be used in major lung cancer studies worldwide.
T16624	Propargyl-PEG4-CH2CH2-Boc		Others
	Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based non-cleavable ADC linker. Propargyl-PEG5-Boc can used to synthesize ADC inhibitors of Galectin-3[1].		Others
T16620	Propargyl-PEG5-acid	Propargyl-PEG4-C2-acid	Others
	Propargyl-PEG5-acid is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG5-acid can used to synthesize ADC inhibitors of Galectin-3[1].		Others