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G3-C12 acetate(848301-94-0 free base)

Catalog No. T11346L CAS T11346L

G3-C12 acetate shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.

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G3-C12 acetate(848301-94-0 free base), CAS T11346L

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Purity: 98%

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Description	G3-C12 acetate shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.
Targets&IC50	galectin-3:(kd)88 nM
In vitro	G3-C12 bearing opolymers N-(2-hydroxypropyl)methacrylamide (HPMA) potently and selectively targets colorectal cancer (CRC) tumour cells over-expressing galectin-3 and displays superior targetability to galectin-3 compared to the galactose bearing copolymer.G3-C12 is a galectin-3 binding peptide, with high affinity (Kd) of 88 nM, but shows no affinity for other galectin family members or to other lectins.

Molecular Weight	1819.03
Formula	C76H119N23O25S2
CAS No.	T11346L

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: Insoluble

H2O: 5 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Kopansky E, et al. Peptide-directed HPMA copolymer-doxorubicin conjugates as targeted therapeutics for colorectal cancer. J Drug Target. 2011 Dec;19(10):933-43.

Related compound libraries

This product is contained In the following compound libraries：

Peptide Compound Library Bioactive Compound Library

Related Products

Related compounds with same targets

TD139 Thiodigalactoside OTX008 GB1107 G3-C12 acetate(848301-94-0 free base)

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Keywords

G3-C12 acetate(848301-94-0 free base) T11346L 免疫与炎症 Galectin G3C12 acetate(848301940 free base) G3 C12 acetate(848301 94 0 free base) G-3-C12 acetate(848301-94-0 free base) Inhibitor inhibitor inhibit

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