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G3-C12 acetate(848301-94-0 free base)

Catalog No. T11346L

G3-C12 acetate shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.

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G3-C12 acetate(848301-94-0 free base) Chemical Structure
G3-C12 acetate(848301-94-0 free base), CAS N/A
Pack Size Availability Price/USD Quantity
1 mg In stock $ 84.00
5 mg In stock $ 205.00
10 mg In stock $ 307.00
25 mg In stock $ 552.00
50 mg In stock $ 793.00
100 mg In stock $ 1,090.00
500 mg In stock $ 2,220.00
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Purity: 95.09%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description G3-C12 acetate shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.
Targets&IC50 GAL3:(kd)88 nM
In vitro G3-C12 bearing opolymers N-(2-hydroxypropyl)methacrylamide (HPMA) potently and selectively targets colorectal cancer (CRC) tumour cells over-expressing galectin-3 and displays superior targetability to galectin-3 compared to the galactose bearing copolymer.G3-C12 is a galectin-3 binding peptide, with high affinity (Kd) of 88 nM, but shows no affinity for other galectin family members or to other lectins.
Molecular Weight 1819.03
Formula C76H119N23O25S2

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Insoluble

H2O: 5 mM

TargetMolReferences and Literature

1. Kopansky E, et al. Peptide-directed HPMA copolymer-doxorubicin conjugates as targeted therapeutics for colorectal cancer. J Drug Target. 2011 Dec;19(10):933-43.

Related compound libraries

This product is contained In the following compound libraries:
Peptide Compound Library

Related Products

Related compounds with same targets
Galectin-3 antagonist 2 OTX008 GB1107 Galectin-3/galectin-8-IN-2 TD139 Galectin-3/galectin-8-IN-1 Thiodigalactoside DB21, Galectin-1 Antagonist

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Keywords

G3-C12 acetate(848301-94-0 free base) Immunology/Inflammation Galectin G3C12 acetate(848301940 free base) G3 C12 acetate(848301 94 0 free base) G-3-C12 acetate(848301-94-0 free base) inhibitor inhibit

 

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