gpr55 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T79721	GPR55 agonist 3
	Compound 26, a GPR55 agonist, exhibits potent activity with EC50 values of 0.239 nM for hGPR55 and 1.76 nM for rGPR55. It also induces β-arrestin recruitment to human GPR55 with an EC50 of 6.2 nM [1].
T79744	GPR55 agonist 4
	GPR55 agonist 4 (Compound 28), with an EC50 of 131 nM for hGPR55 and 1.41 nM for rGPR55, effectively induces β-arrestin recruitment to human GPR55 [1].
TN2268	Tetrahydromagnolol		Cannabinoid Receptor , GPR , GABA Receptor
	Tetrahydromagnolol can activate cannabinoid (CB) receptors.		Cannabinoid Receptor , GPR , GABA Receptor
T22996	ML-191		ERK
	ML-191 is an inhibitor of LPI-induced phosphorylation of ERK1/2.		ERK
T8975	PSB-SB-487		Cannabinoid Receptor
	PSB-SB-487 is antagonist of GPR55.		Cannabinoid Receptor
T8571	ML-184	CID2440433	Cannabinoid Receptor
	ML-184 (CID2440433) is a potent synthetic agonist of GPR55 with EC50 of 0.26 μM.		Cannabinoid Receptor
T22103	ML-193	CID 1261822	Cannabinoid Receptor
	ML-193 (CID 1261822) is a potent and selective GPR55 antagonist( IC50 : 221 nM). It shows more than 27-fold selectivity for GPR55 over GPR35, CB1 and CB2, and can improve the motor and the sensorimotor deficits of Parkin...		Cannabinoid Receptor
T4478	CID 16020046	C390-0219	Cannabinoid Receptor
	CID 16020046 (C390-0219) is a selective GPR55 antagonist, inhibiting GPR55 constitutive activity with IC50 of 0.15 μM in yeast.		Cannabinoid Receptor
T14046	Anandamide	(5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide	Cannabinoid Receptor , Endogenous Metabolite
	Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55) in the central nervous sy...		Cannabinoid Receptor , Endogenous Metabolite
T1915	AM251		Cannabinoid Receptor , GPR
	AM251 is a effective CB1 receptor antagonist (IC50/Ki: 8 /7.49 nM) that displays 306-fold selectivity over CB2 receptors; also effective GPR55 agonist (EC50: 39 nM).		Cannabinoid Receptor , GPR
T23097	O-1602	O1602,O 1602	Cannabinoid Receptor , Calcium Channel
	O-1602 is a novel GPR55 agonist, an atypical cannabinoid associated with the central nervous system and obesity, and is a candidate compound for the treatment of cystitis.O-1602 promotes hepatic steatosis through GPR55 a...		Cannabinoid Receptor , Calcium Channel
T33452	ML192	ML-192,CID1434953,CID 1434953,ML 192,CID-1434953	Cannabinoid Receptor , GPR , Arrestin
	ML192 (CID1434953) is a selective GPR55 ligand antagonist. ML192 is an inhibitor that inhibits β-arrestin transport, ERK1/2 phosphorylation, and PKCβII translocation.		Cannabinoid Receptor , GPR , Arrestin
T27017	CID1792197	CID 1792197,CID-1792197
	CID1792197 is a selective agonist of GPR55.
T27483	GSK575594A	GSK-575594A,GSK 575594A
	GSK575594A is a selective agonist of GPR55.
T22539	Abn-CBD		Others
	GPR55 cannabinoid receptor agonist		Others
T27016	CID1172084	CID-1172084,CID 1172084
	CID1172084, a novel high-potent GPR55 agonist, interacts with cannabinoid receptors.
T27480	GSK494581A	GSK 494581A,GSK-494581A
	GSK494581A is a GPR55 agonist and glycine transporter subtype 1 inhibitor.
T68688	CID-1792579
	CID-1792579 is a selective agonist of GPR55.
T77212	L-α-lysophosphatidylinositol (Soy) (sodium)
	L-α-Lysophosphatidylinositol Soy Sodium, an endogenous ligand of GPR55, is an endocannabinoid neurotransmitter and lysophospholipid. This compound falls within the class of lysophospholipids [1].
T68247	PSB-KD107
	PSB-KD107 is an agonist of the Cannabinoid-Activated Orphan G‑Protein-Coupled Receptor GPR18. PSB-KD107 displayed significantly higher potency and efficacy than THC, determined in a GPR18-dependent β-arrestin recruitment...