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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T37548 | Azido-FTY720 | azido-FTY720 | |
FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analog of sphingosine. It is a novel immune modulator that prolongs allograft transplant survi... | |||
T2539 | Fingolimod hydrochloride | Fingolimod (FTY720) HCl,FTY720 | TRP/TRPV Channel , S1P Receptor , PAK , LPL Receptor |
Fingolimod hydrochloride (FTY720) , a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: 0.033 nM in K562 and NK cells). | |||
T15354 | FTY720 (S)-Phosphate | (S)-FTY720 phosphate,(S)-FTY720P | Others |
FTY720 (S)-Phosphate is an S1P receptor 1 (S1PR1) agonist. It is used in the research of acute inflammatory diseases such as acute lung injury. | |||
T70816 | (R)-FTY720-OMe | ||
(R)-FTY720-OMe is a structural analogue of FTY720 which acts as a specific competitive inhibitor of sphingosine kinase 2 (SK2). Furthermore, (R)-FTY720-OMe does not inhibit sphingosine kinase 1 (SK1) activity. | |||
T20153 | FTY720-C2 | FTY 720 C 2,FTY-720-C-2 | |
FTY720-C2 is an FTY720 analog. It acts as an effective stimulator of the activity of the protein phosphatase 2A. | |||
T31882 | FTY720-Mitoxy | FTY 720 Mitoxy,FTY-720-Mitoxy | |
FTY720-Mitoxy is an FTY720 analog that can be uesd as a novel stimulator of the activity of the protein phosphatase 2A (PP2A), targeting mitochondria. | |||
T78091 | (S)-FTY720-phosphonate | LPL Receptor | |
FTY720 (S)-Phosphate, an S1P receptor 1 (S1PR1) agonist, is utilized in studying acute inflammatory diseases, including acute lung injury. | |||
T9744 | MP07-66 | Phosphatase | |
MP07-66 is a novel FTY720-analog devoid of immunosuppressive effects leads to the reactivation of PP2A, which in turn triggers apoptosis of CLL cells. | |||
T7939 | Fingolimod | FTY-720A,FTY-720 | S1P Receptor , PAK , LPL Receptor |
Fingolimod (FTY-720A) is an antagonist of sphingosine 1-phosphate (S1P) (IC50 of 0.033 nM in K562 and NK cells). |